Clinical Trials Logo

Prolapse clinical trials

View clinical trials related to Prolapse.

Filter by:

NCT ID: NCT04008654 Completed - Clinical trials for Urinary Incontinence

Evaluation of the Benefits of Enhanced Recovery After Surgery (ERAS) Protocol in Pelvic Prolapse

Start date: July 5, 2019
Phase: N/A
Study type: Interventional

ERAS protocols have been shown to improve recovery in terms of reduced pain, shortened time to ambulation and length of hospital stay. This study aims to investigate the impact of ERAS protocol on time to mobilization and length of hospital stay in patients undergoing surgery for urinary incontinence and pelvic prolapse.

NCT ID: NCT04002648 Completed - Prolapse; Mitral Clinical Trials

Minimally Invasive or Conventional Edge-To-Edge Repair for Severe Mitral Regurgitation Due to Bileaflet Prolapse in Barlow's Disease: Does the Surgical Approach Have an Impact on the Long-term Results?

Start date: December 1, 2016
Phase:
Study type: Observational

The study evaluates the long-term results of patients affected by bileaflet prolapse in Barlow's Disease, treated with edge-to-edge technique between 1997 and 2011.

NCT ID: NCT04002375 Not yet recruiting - Apical Prolapse Clinical Trials

Posterior Approach for Pectouteropexy

Start date: June 30, 2019
Phase: Phase 4
Study type: Interventional

Pectouteropexy surgery has lower complication rates compared to other sling operations. Sacrocolpopexy is another common procedure for hanging the uterus. Small bowel obstruction, ileus or defecation problems are observed in percentages ranging from 0.1 to 5%. Mesh placed between sacrum and vagina often causes narrowing of the pelvis, adhesions may occur and traumas may occur in hypogastic nerves. However, presacral bleeding, which is the most feared complication of these operations, is a rare but life-threatening condition. In pectouteropexy, it is located away from the bladder, intestine and hypogastric vessels by placing the iliopectineal ligament laterally and eliminates the risk of presacral hemorrhage. In pectouteropexy surgery, the mesh is placed anterior to the cervix. The points emphasized in the criticisms about this technique, inadequate support of the posterior compartment mesh placed in anterior in a future pregnancy is a possible cesarean section and the negative effects on the delivery process. Therefore, a new technique of pectouteropexy surgery to the posterior of the cervix instead of the anterior cervix of the cervix, the sacrouterine ligament to reduce the complications that may occur due to this procedure and this study was planned to increase the effectiveness.

NCT ID: NCT03995797 Not yet recruiting - Clinical trials for Pelvic Organ Prolapse

VESPER: Pelvic Organ Prolapse Study

VESPER:POP
Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Patients seen with Stage 1-2 pelvic organ prolapse (POP) who have failed conservative treatments will be offered to participate in a sham controlled RCT of outpatient therapy with the Fotona Smooth Erbium Yag Laser. Patients will be randomised to either outpatient laser treatments or sham treatments. Patients will be blinded to which arm they have been randomised. Patients will be asked to complete appropriate relevant symptom and quality of life questionnaires and prolapse scoring, prior to treatment and at each monthly treatment and then 6 and 12 months following the final treatment. At 6 months following final treatment, Sham patients will be un-blinded and offered the laser therapy if they wish.

NCT ID: NCT03995641 Terminated - Postoperative Pain Clinical Trials

The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixation

Start date: February 2, 2019
Phase: Phase 4
Study type: Interventional

This study will randomize patients to either receive intraoperative administration of local anesthetic and corticosteriod at time of sacrospinous ligament fixation compared to placebo to determine if intraoperative trigger point injection (TPI) improves postoperative gluteal and sciatic pain scores along with use of narcotic pain medications. There is a paucity of data examining interventions to potentially ameliorate the postoperative gluteal pain often associated with sacrospinous ligament colpopexy. Our study aims to determine if a compounded TPI improves postoperative pain scores and minimizes use of narcotic pain medications by 20% compared to controls.

NCT ID: NCT03991455 Completed - Clinical trials for Pelvic Organ Prolapse

Evaluation of Safety and Efficacy of the Apyx™ Device for the Repair of Pelvic Organ Prolapse (POP)

Start date: October 25, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to further evaluate this minimally invasive SSLF technique with respect to safety, clinical effectiveness, and patient satisfaction. The procedure will be performed in women electing to undergo surgical repair of their prolapse who wish to preserve their uterus, and will be evaluated using standardized measures and questionnaires.

NCT ID: NCT03988569 Completed - Clinical trials for Pelvic Organ Prolapse

Enhanced Consent and Preparedness for Surgery Trial

ECAPS
Start date: July 1, 2019
Phase: N/A
Study type: Interventional

To develop an audiovisual decision aid (AVDA) to improve the informed consent process. The investigators aim to examine the impact of a comprehensible AVDA that is written below the 8th grade reading level. The AVDA would be used for surgical consent compared to traditional verbal consent. Additionally, the investigators plan to determine whether this effect varies across the measured levels of health literacy of our patients.

NCT ID: NCT03973281 Recruiting - Clinical trials for Pelvic Organ Prolapse

EASE: The Materna Prep Pivotal Study

Start date: December 11, 2019
Phase: N/A
Study type: Interventional

This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Subjects are randomized to Materna Prep Device or Standard of Care without use of the Materna Prep Device Intervention with the Materna Prep Device is expected to be a one-time use of approximately 30-90 minutes during the 1st stage of labor. Subject participation in the study is targeted to be 12 months from the time of the use of the device during delivery.

NCT ID: NCT03966469 Completed - Surgery Clinical Trials

What is the Impact of the Presence of a Support Person on Informed Consent

Start date: May 17, 2019
Phase:
Study type: Observational

In practice, the Investigators recommend that patients bring a family member or close friend to their pre-operative appointment to help with patient anxiety, comprehension, and informed decision-making. However, there is limited literature to support this recommendation. The investigators are exploring if having a support person present during this consent process impacts anxiety, satisfaction, knowledge, and preparedness for surgery.

NCT ID: NCT03962075 Completed - Prolapse, Vaginal Clinical Trials

Short-term Outcomes of Laparoscopic Repair of Paravaginal Defects

Start date: August 1, 2016
Phase: N/A
Study type: Interventional

this study designed To evaluate the efficacy and outcomes of laparoscopic approach for repair of paravaginal defects associated with anterior vaginal wall prolapse.