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Prodromal Bone Deterioration clinical trials

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NCT ID: NCT02155595 Completed - Osteoporosis Clinical Trials

Pathogenesis of Atypical Femur Fractures on Long Term Bisphosphonate Therapy

NIH fracture
Start date: May 2014
Phase:
Study type: Observational

The purpose of this protocol is to determine the risk of atypical femoral shaft (thigh bone) fractures after long term fracture prevention therapy with a class of drugs called "bisphosphonates", colloquially referred to as Alendronate, risedronate, Ibandronate, and Zoledronate. In addition, the study is designed to find out which patient is most likely to develop this potential life changing complication and why. Finally, the results of this study will help clinicians to better understand the reason and thus tailor patient specific treatments…i.e., "the right treatment for the right patient for right duration."