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Clinical Trial Summary

This single blinded parallel randomized clinical trial will be conducted on 50 patients presented to Emergency Department of Alexandria Main University Hospital who are indicated for procedural sedation. All patients included in the study will be allocated randomly using computer software with concealment of randomization in to two groups: - Group A: 25 patients will receive ketamine (0.5 mg/kg) plus midazolam (0.05 mg/kg) - Group B: 25 patients will receive ketamine (0.5 mg/kg) plus propofol (0.5 mg/kg) Additional ketamine (0.25 mg/kg) will be administered in case of inadequate sedation in both groups. the two groups will be compared as regard incidence of complications World Society of Intravenous Anesthesia (SIVA) international sedation task force to standardize reporting adverse events


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06368219
Study type Interventional
Source Alexandria University
Contact Asmaa Ramadan
Phone 01274627276
Email a_ramadan15@alexmed.edu.eg
Status Not yet recruiting
Phase Early Phase 1
Start date April 2024
Completion date October 2024

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