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Detoxification of the Liver In PSC (Dolphin) — DOLPHIN  

Primary Sclerosing Cholangitis Clinical Trial

Official title:
Detoxification of the Liver in Primary Sclerosing Cholangitis

Clinical Trial Summary

This study is a clinical trial being done to investigate the efficacy of drug BRS201 as a treatment in patients with primary sclerosing cholangitis. Participation in this study will take 8 weeks long and the study is structured as a cross-over study in which participants will take the study drug for 4 weeks and a placebo drug for 4 weeks in a randomized order in the form of an oral medication. Participation may also involve receiving an IV dose of the medication. The study will require participants to attend 9 study visits, all of which will be remote. Participation will involve taking an oral medication twice daily, tracking the medication in a log, and getting blood drawn and giving a stool sample for a few lab tests throughout the study. For the lab tests, a research nurse will visit the participant in-home for the convenience of the participant.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05835505
Study type Interventional
Source Brigham and Women's Hospital
Contact Joshua Korzenik, MD
Phone 617 732-6389
Email jkorzenik@bwh.harvard.edu
Status Recruiting
Phase Phase 2
Start date December 12, 2023
Completion date December 1, 2025
View Details
See also
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