Clinical Trials Logo

Clinical Trial Summary

This study is working to research the efficacy and significant of the anti-virus therapy in the unresectable Hepatitis B virus (HBV) related primary liver cancer(PLC) so as to establish treatment standards of anti-virus therapy in PLC.


Clinical Trial Description

primary liver cancer(PLC)is one of the world's most common malignancies, especially in East-Asian countries.Hepatitis B virus (HBV) infection is associated with 70-90% of PLC cases in China. PLC can develop during any stage of the natural course of chronic HBV infection and anti-virus therapy should be considered during the management of PLC. However, there is no definite guide on when or how to practice the anti-virus therapy, especially in unresectable or inoperable PLC. Because of these facts, research on the significant of the anti-virus therapy in the HBV-related PLC is urgently needed.

200 patients will be randomly assigned to anti-virus therapy group and control gruop.The time to progression(TTP) and overall survival within two years will be used to evaluate the effect of anti-virus therapy on PLC.

The aim of this study is to research the efficacy and significant of the anti-virus therapy in the unresectable HBV-related PLC so as to establish treatment standards of anti-virus therapy in PLC. ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00824707
Study type Interventional
Source Eastern Hepatobiliary Surgery Hospital
Contact
Status Completed
Phase N/A
Start date December 2008
Completion date December 2010

See also
  Status Clinical Trial Phase
Active, not recruiting NCT03161925 - Chinese Liver Cancer Clinical Survey N/A
Completed NCT00261378 - Prospective Randomised Study of Doxorubicin in the Treatment of Hepatocellular Carcinoma by Drug-Eluting Bead Embolisation Phase 2
Enrolling by invitation NCT05609448 - MRI-guided Holmium-166 Radioembolization N/A
Recruiting NCT05714124 - Liver Embolization Approaches for Tumor Management
Not yet recruiting NCT05353894 - Effect of Food and Formulation on the Pharmacokinetics, Safety, and Tolerability of GNS561 After One Single Dose (50 and 200mg) in Healthy Volunteers Phase 1
Completed NCT03518632 - Preoperative Physical Activity Intervention in Patients Before Planned Liver Resection for Cancer (APACHE) N/A
Terminated NCT00003530 - Antineoplaston Therapy in Treating Patients With Primary Liver Cancer Phase 2
Recruiting NCT04806464 - Clinical Study of VG161 in Subjects With Advanced Primary Liver Cancer Phase 1
Recruiting NCT06342414 - An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer
Completed NCT01116804 - Role PET Imaging in Response Assessment for Hepatocellular Carcinoma (HCC) Phase 1
Recruiting NCT03067493 - RFA or Surgical Resection Combined With Neo-MASCT for Primary HCC: a Phase II Trial Phase 2
Completed NCT05183776 - Clinical Validation of a Fractional Administration Device for Holmium-166 SIRT N/A
Not yet recruiting NCT06430983 - Recurrent Liver Cancer: Reconceptualization and Reevaluation
Recruiting NCT05677724 - Single-cell RNA Sequencing Resolves the Regulatory Role of HBV on the Hepatocellular Carcinoma Immune Microenvironment
Not yet recruiting NCT03178929 - Effect of SAMe Treatment on Recurrence After Radical Treatment of Primary Hepatic Carcinoma N/A
Recruiting NCT05267080 - Registry on Percutaneous Electrochemotherapy
Not yet recruiting NCT02327819 - The Effect of Branched-chain Amino Acid (BCAA) on the Progression of Primary Liver Cancer N/A
Completed NCT01640522 - Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms N/A
Completed NCT00408122 - Evaluation of Preoperative Investigations in Patients With Liver Cancer N/A
Recruiting NCT03297255 - Primary Liver Cancer Cohort of South China N/A