Prevalence of Primary Aldosteronism in Young Adults With Acute Stroke

Primary Aldosteronism Clinical Trial

Official title:

Prevalence of Primary Aldosteronism in Young Adults With Acute Stroke

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04203420
• Other study ID #: PASTROKE
• Status: Completed
• Start date: July 1, 2017
• Est. completion date: December 13, 2019

Study information

• Verified date: December 2019
• Source: Chongqing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The guideline requires clinical works to screen for primary aldosteronism(PA) in young adults with family history of stroke at early onset. But the prevalence of PA in young adults with stroke onset before 45 years old had never been investigated. The study aimed to discover the prevalence as well as the clinical characteristics between patients with PA and those without PA during stroke attack. In order to fulfill this objective, investigators intended to conduct a cross-sectional study by taking screening and confirmatory tests among young adults who once admitted due to early onset of acute stroke.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 116
• Est. completion date: December 13, 2019
• Est. primary completion date: November 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• patients who were once admitted in the First affiliated hospital of Chongqing Medical university(CQMU), with stroke onset less than two weeks

Exclusion Criteria:

death, serious sequela with motor, comprehensive or linguistic dysfunction, patients unwilling to join in, etiology of trauma, infective or tumor disease, patients with impaired cardiac, renal or liver function during admission-

Related Conditions & MeSH terms

• Hyperaldosteronism
• Primary Aldosteronism
• Stroke

Intervention

Other:
• screening and confirmatory tests
screening test is a blood test of the ratio of plasma aldosterone concentration(PAC) and direct renin concentration(DRC), confirmatory test is Captopril Challenge test

Locations

Country	Name	City	State
China	The First Affilated Hospital of Chongqing Medical University	Chongqing	Chongqing

Sponsors (1)

Lead Sponsor	Collaborator
Chongqing Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	prevalence of PA	to find out the proportion of PA patients in young adults with early onset of acute stroke	through study completion, an average of 2 years