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To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis — OPTIM-PTL  

Preterm Birth Clinical Trial

Official title:
To Optimize Antenatal Management of Women Admitted With Pre Term Labor and Intact Membranes Using Multivariable Prediction Models: Multicenter Randomised Control Trial (OPTIM-PTL)

Clinical Trial Summary

Implementation of prediction models of risk of spontaneous delivery within 7 days or of intra-amniotic infection in women with preterm labor and intact membranes

Clinical Trial Description

To evaluate whether the implementation of prediction models of risk of spontaneous delivery within 7 days or of intra-amniotic infection: 1. Optimises antenatal management (regarding steroids, tocolysis, antibiotics, maternal length stay duration) without worsening perinatal outcomes. 2. It is a cost-effective strategy. 3. It improves neonatal outcome (in premature newborns <30 weeks), and reduces infectious maternal morbility. 4. It improves neurodevelopmental outcome at 1.2 and 5 years. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04831086
Study type Interventional
Source Fundacion Clinic per a la Recerca Biomédica
Contact Teresa Cobo, MD,PhD
Phone +34 93 227 54 00
Email tcobo@clinic.cat
Status Recruiting
Phase Phase 3
Start date May 5, 2021
Completion date December 30, 2023
View Details
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