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Cerclage After Full Dilatation Caesarean Section — CRAFT  

Preterm Birth Clinical Trial

Official title:
An Investigation Into the Role of Previous in Labour Caesarean Section in Future Preterm Birth Risk and Management Strategies

Clinical Trial Summary

CRAFT-OBS: Observational Study; To evaluate subsequent pregnancy risk of preterm birth in women with a history of previous caesarean in established labour. This prospective study using clinically acquired cervical length and quantitative fetal fibronectin data will help establish a predictive model of preterm birth <34 weeks and <37 weeks. CRAFT-RCT: Randomised controlled trial arm; To assess treatment for short cervix in women at high risk of preterm birth following a caesarean section at full dilatation CRAFT-IMG: Imaging sub-study; To aid understanding of micro and macrostructural features within the cervix which predisposes to preterm birth in women with a previous full dilatation caesarean section. This will use MRI and an advanced transvaginal ultrasound protocol and to assess if structural changes can be visualised in the cervix.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04110704
Study type Interventional
Source Guy's and St Thomas' NHS Foundation Trust
Contact Agnieszka Glazewska-Hallin
Phone 020 7188
Email agnieszka.glazewska-hallin@kcl.ac.uk
Status Recruiting
Phase N/A
Start date October 2, 2019
Completion date October 1, 2022
View Details
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