Effect of Ginseol Kg1 on Blood Pressure Lowering

Status Recruiting

Clinical Trial Summary

In this study, we investigate the effects of Ginseol Kg1 (Korea red ginseng extract) on blood pressure in prehypertensive or stage I hypertensive patients.

Clinical Trial Description

This is a multicenter, randomized, placebo-controlled, double-blind study. At the end of an initial 2-week washout period, patients fulfilling the inclusion criteria are assigned to three groups, i.e. control group (placebo), low dose Ginseol Kg1 group (100mg), or high dose Ginseol Kg1 (300mg) group. They will intake the study drug for 8 weeks. 24-h ambulatory BP monitoring (ABPM) and pulse wave velocity are measured at the end of the washout period and after 8 weeks of active treatment. At each visit, seated SBP and DBP, heart rate, use of concomitant medication and spontaneously reported adverse events are recorded. Compliance with medication (determined by counting returned tablets) is evaluated at each visit. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01483430
Study type	Interventional
Source	Seoul National University Hospital
Contact	Kwang-il Kim, MD, PhD
Phone	+82-31-787-7032
Email	kikim907@snu.ac.kr
Status	Recruiting
Phase	Phase 3
Start date	September 2011
Completion date	December 2012

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03644524` - Heat Therapy and Cardiometabolic Health in Obese Women	N/A
Completed	`NCT02551640` - Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients	N/A
Terminated	`NCT01295216` - Use of Mobile Technology to Prevent Progression of Pre-hypertension in Latin American Urban Settings	N/A
Completed	`NCT01637909` - Korean Life-Style Modification Effects on Blood Pressure	N/A
Unknown status	`NCT01308983` - Study of Amiloride on Vascular Phenotypes in Young Adults With Prehypertension	Phase 4
Active, not recruiting	`NCT03596099` - Rice Vinegar as an Intervention to Lower Blood Pressure in Adults With Prehypertension and 10-year CVD Risk <10%	N/A
Completed	`NCT04326686` - Measuring Individual Responses to a Wholegrains and Nuts Intervention to Reduce Blood Pressure in Prehypertension	N/A
Completed	`NCT03898518` - The Effects of a Jump Rope Exercise Program on Body Composition and Self-efficacy in Obese Adolescent Girls	N/A
Terminated	`NCT01983462` - Vascular Dysfunction in Human Obesity Hypertension	Phase 2
Completed	`NCT01458496` - Health Coaching to Effect Lifestyle Behaviour Change	N/A
Completed	`NCT01472692` - Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure	Phase 4
Completed	`NCT03266510` - Inspiratory Muscle Strength Training to Improve Blood Pressure and Physiological Function	N/A
Completed	`NCT02998840` - A Prospective Study of B244 Delivered as a Topical Spray to Determine Safety and Efficacy in Subjects With Elevated Blood Pressure	Phase 2
Completed	`NCT01974570` - Effect and Safety of Marealis RPC (Refined Peptide Concentrate) in Mild or Moderate Hypertensive Subjects	Phase 2
Completed	`NCT02326766` - Blood Pressure Lowering Effect of Supplementation With Korea Red Ginseng Associated With Reductions in Circulating Lp-PLA2 Activity and Lysophospatidylcholines and an Increase in Dihydrobiopterin in Prehypertensive Subjects	Phase 3
Completed	`NCT01395329` - Nebivolol and the Endothelin (ET)-1 System	Phase 4
Completed	`NCT01331486` - Nitric Oxide Mediated Vasodilatory Response to Hawthorn Standardized Extract	Phase 1
Completed	`NCT05274971` - Diet and Exercise on Ambulatory Blood Pressure	N/A
Active, not recruiting	`NCT02371317` - Stress Management for High Blood Pressure	N/A
Completed	`NCT03006471` - Effect of Dapagliflozin on Blood Pressure Variability in Prediabetes and Prehypertension	Phase 4