Clinical Trials Logo
  1. Home
  2. Pregnancy
  3. NCT04429178
  4. Details
NCT04429178 Clinical Trial

Portal Vein Pulsatility Flow in Pregnancy

Pregnancy Clinical Trial

Official title:
Portal Vein Pulsatility Flow in Pregnancy - a Pilot Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04429178
Other study ID # 2020-00774; qu19Buddeberg
Secondary ID
Status Completed
Phase
First received
Last updated
Start date August 13, 2020
Est. completion date March 1, 2022

Study information
Verified date March 2022
Source University Hospital, Basel, Switzerland
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study is to investigate if portal vein pulsatility fraction can be measured in pregnancy and if it increases during the course of pregnancy as would be expected by the physiologic increase in blood volume that happens during pregnancy. Portal vein pulsatility fraction is measured in non-pregnant controls and in women in the 1st, 2nd and 3rd trimester of pregnancy.

Recruitment information / eligibility
Status Completed
Enrollment 80
Est. completion date March 1, 2022
Est. primary completion date March 1, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria: - Ability to give informed consent - American Society of Anesthesiologists (ASA) Class I and II - Singleton pregnancy during 1st, 2nd or 3rd trimester or healthy non-pregnant females of childbearing age as controls Exclusion Criteria: - Inability to give informed consent - Multiple gestation - Significant co-morbidities (e.g. cardiac abnormalities, cardiac dysfunction, arrhythmias, severe asthma, renal insufficiency) - High risk pregnancies (e.g. pre-eclampsia, gestational hypertension, HELLP, gestational diabetes) - Body-Mass-Index (BMI) < 18kg/m2 or >40kg/m2

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• ultrasound
portal vein pulsatility fraction (percent) measured with ultrasound

Locations
Country Name City State
Switzerland Department of Anesthesiology, University Hospital Basel Basel

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Basel, Switzerland

Country where clinical trial is conducted

Switzerland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Portal vein pulsatility fraction (percent) Portal vein pulsatility fraction (percent) single time-point at baseline
Secondary Inferior vena cava diameter (mm) Inferior vena cava diameter (mm) single time-point at baseline
Secondary Inferior vena cava collapsibility index (percent) Inferior vena cava collapsibility index (percent) single time-point at baseline
Secondary Hepatic venous flow (cm/sec) Hepatic venous flow (cm/sec) single time-point at baseline
Secondary Right atrial and ventricular dimensions (cm) Right atrial and ventricular dimensions (cm) single time-point at baseline
Secondary Tricuspid Annular Plane Systolic Excursion (TAPSE) (mm) Tricuspid Annular Plane Systolic Excursion (TAPSE) (mm) single time-point at baseline
See also
  Status Clinical Trial Phase
Completed NCT03442582 - Afluria Pregnancy Registry
Terminated NCT02161861 - Improvement of IVF Fertilization Rates, by the Cyclic Tripeptide FEE - Prospective Randomized Study N/A
Not yet recruiting NCT05934318 - L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE) N/A
Enrolling by invitation NCT05415371 - Persistent Poverty Counties Pregnant Women With Medicaid N/A
Completed NCT04548102 - Effects of Fetal Movement Counting on Maternal and Fetal Outcome Among High Risk Pregnant Woman N/A
Completed NCT03218956 - Protein Requirement During Lactation N/A
Completed NCT02191605 - Computer-delivered Screening & Brief Intervention for Marijuana Use in Pregnancy N/A
Completed NCT02223637 - Meningococcal Quadrivalent CRM-197 Conjugate Vaccine Pregnancy Registry
Recruiting NCT06049953 - Maternal And Infant Antipsychotic Study
Completed NCT02577536 - PregSource: Crowdsourcing to Understand Pregnancy
Not yet recruiting NCT06336434 - CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy Phase 1/Phase 2
Not yet recruiting NCT05412238 - Formulation and Evaluation of the Efficacy of Macro- and Micronutrient Sachets on Pregnant Mothers and Children Aged 6-60 Months N/A
Not yet recruiting NCT04786587 - Alcohol Self-reporting During Pregnancy. AUTOQUEST Study.
Not yet recruiting NCT05028387 - Telemedicine Medical Abortion Service Using the "No-test" Protocol in Ukraine and Uzbekistan.
Completed NCT02783170 - Safety and Immunogenicity of Simultaneous Tdap and IIV in Pregnant Women Phase 4
Completed NCT02683005 - Study of Hepatitis C Treatment During Pregnancy Phase 1
Recruiting NCT02564250 - Maternal Metabolism and Pregnancy Outcomes in Obese Pregnant Women N/A
Recruiting NCT02619188 - Nutritional Markers in Normal and Hyperemesis Pregnancies N/A
Recruiting NCT02507180 - Safely Ruling Out Deep Vein Thrombosis in Pregnancy With the LEFt Clinical Decision Rule and D-Dimer
Terminated NCT02537145 - PregnanT Moms Measure - Do-It-Yourself Health Monitoring and Simulation of Health in Pregnant Women