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NCT02381106 Clinical Trial

The ADRB3 Receptor in Pregnancy

Pregnancy Complications Clinical Trial

Official title:
The ADRB3 Adrenergic Receptor - a Possible New Target for Controlling Pre-eclampsia and Hypertension in Pregnancy and Uterine Contractions in Non-pregnant and Pregnant Myometrium

Clinical Trial Details — Status: Suspended

Administrative data
NCT number NCT02381106
Other study ID # VAI
Secondary ID
Status Suspended
Phase
First received
Last updated
Start date November 2014
Est. completion date December 2029

Study information
Verified date May 2023
Source Karolinska Institutet
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The primary overall objective of this study is to characterize the levels of and compare levels of the ADRB3 receptor in human non-pregnant myometrium, pregnant myometrium at different time points in pregnancy, in normal and dysfunctional labor and also to measure levels and expression of these receptors in placental arteries at different maturation statuses of placenta and in pre-eclampsia/hypertension

Recruitment information / eligibility
Status Suspended
Enrollment 80
Est. completion date December 2029
Est. primary completion date December 2028
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 50 Years
Eligibility Inclusion Criteria: - Women undergoing cesarian section Exclusion Criteria: - Interkurrent diseases

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Sweden Dept of Obstetrics and Gynecology, Danderyd Hospital Stockholm

Sponsors (1)
Lead Sponsor Collaborator
Karolinska Institutet

Country where clinical trial is conducted

Sweden, 

Outcome
Type Measure Description Time frame Safety issue
Primary characterization of the levels of the ADRB3 receptor in human pregnant myometrium 1 month
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