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Clinical Trial Summary

The purpose of this study is to understand if administration of a personalized dose of the anti-hypertensive medication, labetalol, based on patient's body-mass index, will be more effective at controlling severe hypertension during pregnancy, compared to the current standard dosing.


Clinical Trial Description

The investigators seek to asses the effect of obesity (BMI>30) on severe hypertension control in patients with preeclampsia with severe features. The investigators hypothesize that successive administration of 40-60-80 mg of labetolol will reduce time to blood pressure control versus the standard dosing, 20-40-80 mg labetolol, recommended by the American College of Obstetricians and Gynecologists in 2015. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03872336
Study type Interventional
Source Albany Medical College
Contact
Status Terminated
Phase Phase 4
Start date February 18, 2019
Completion date July 20, 2020

See also
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Completed NCT05096728 - Nifedipine Dosing Daily vs Twice a Day for Pre-eclampsia With Severe Features (NOPPI)