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Effect of Metformin on Healthy Live Birth in Women With Prediabetes — MELT-PreDM  

Prediabetes Clinical Trial

Official title:
Effect of Metformin on Healthy Live Birth After In-vitro Fertilization in Women With Prediabetes Mellitus: a Multicenter Double-blind Placebo Controlled Randomized Trial

Clinical Trial Summary

To evaluate the efficacy and safety of metformin pretreatment on reproductive outcomes in infertile women with prediabetes.

Clinical Trial Description

To evaluate the efficacy and safety of metformin pretreatment on reproductive outcomes in infertile women with prediabetes and to determine whether either starting metformin pretreatment before ovarian stimulation (aiming at improving the quality of oocyte/embryo) or starting before frozen embryo transfer (FET) (aiming at improving the receptivity of endometrium) could increase the chance of a healthy live birth compared with placebo. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06064669
Study type Interventional
Source Shandong University
Contact Zi-Jiang Chen, Professor
Phone +0086 531 85651190
Email chenzijiang@vip.163.com
Status Recruiting
Phase N/A
Start date February 22, 2024
Completion date December 31, 2027
View Details
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