Prediabetes Clinical Trial
Our aim is to investigate the effects of a 12-week structured aerobic exercise on fasting and 2 h glucose, insulin and lipid concentrations in sedentary overweight subjects in whom impaired fasting glucose and/or impaired glucose tolerance was observed for the first time.
Study type: Interventional
Study design: Randomized
Endpoint classification: Changes in fasting and 2 h glucose, insulin and lipid
concentrations
Intervention model: Parallel assignment
Masking: Open label
Primary purpose: Prevention and dose response assessment of exercise on glucose and lipid
metabolism
Condition: Prediabetes
Intervention: Supervised exercise - The training sessions of the intervention group are
carried out indoors 3 times a week for 3 months and supervised by an exercise instructor and
physician. Each session last for 60 min and include a 5-min warm-up and stretching, a 20-min
walking at speeds 2-4 km/h depending of the participant's physical condition, a 5-min
stretching and balance training, a 20-min walking, and a 10-min stretching and balance
training. After 1.5 months the 5-min stretching and balance training between the two 20-min
walkings is excluded, and the walking time become 45 min.
No intervention: control group; couseling at baseline. Participants of the control group are
advised to continue their usual physical and dietary habits.
Experimental: 1 -supervised exercise intervention. No intervention: 2 - standard counseling
at baseline.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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