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Open-Label Duloxetine Monotherapy in the Treatment of Posttraumatic Stress Disorder

Posttraumatic Stress Disorders Clinical Trial

Official title:
A Study of the Effectiveness and Tolerability of Duloxetine (Cymbalta) in the Treatment of PTSD.

Clinical Trial Summary

The purpose of this study is to determine whether Duloxetine (Cymbalta®) is an effective treatment in reducing the symptoms of Posttraumatic Stress Disorder (PTSD).

Clinical Trial Description

Duloxetine has established efficacy for treatment of major depression, generalized anxiety disorder and diabetic peripheral neuropathic pain. Chronic PTSD is often treated with antidepressants, in fact there are only two FDA-approved treatments for PTSD. Yet many chronic PTSD patients, especially male combat veterans, have a limited response to antidepressant treatment (Baker et al, 1995; Cañive et al, 1998; Hertzsberg et al 2000) and new pharmacotherapies should be investigated. ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00583193
Study type Interventional
Source New Mexico VA Healthcare System
Contact Lawrence A Calais, R.N.
Phone 505-265-1711
Email lawrence.calais@va.gov
Status Recruiting
Phase Phase 3
Start date December 2005
Completion date June 2008
View Details
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