Comparing Imaginal Exposure and Imagery Rescripting in Treatment of Posttraumatic Stress Disorder (PTSD)

Posttraumatic Stress Disorder Clinical Trial

Official title:

Comparing Imaginal Exposure (IE) and Imagery Rescripting and Reprocessing Therapy (IRRT) in the Treatment of Posttraumatic Stress Disorder (PTSD)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00891098
• Other study ID #: 2-Hoffart
• Status: Completed
• Phase: N/A
• First received: April 30, 2009
• Last updated: June 4, 2013
• Start date: November 2008
• Est. completion date: November 2012

Study information

• Verified date: June 2013
• Source: Modum Bad
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway:National Committee for Medical and Health Research Ethics
• Study type: Interventional

Clinical Trial Summary

The outcome of trauma treatment (Posttraumatic Stress Disorder - PTSD) may be influenced by which emotions that are predominant among current symptoms, e.g. fear, anger, guilt, shame. Different treatment procedures for processing traumatic memories may resolve different emotions. This study compares two different treatment procedures of working with trauma memories in PTSD treatment (namely, Imaginal Exposure and Imagery Rescripting) in order to test this.

Description:

The main objectives of this study are:

1. To assess the relative efficacy of the two procedures in inpatient treatment for PTSD

2. To assess whether the predominant emotions in the traumatic memories moderate the outcome of the different procedures

3. To assess whether theory-derived constructs mediate outcome and whether the mediating relationships are different in the two treatments

4. To provide a theoretical account of the two models

5. To psychometrically evaluate 3 new measures

Recruitment information / eligibility

• Status: Completed
• Enrollment: 65
• Est. completion date: November 2012
• Est. primary completion date: November 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years to 65 Years

Eligibility

Inclusion Criteria:

• DSM-IV diagnosis of PTSD identified as primary diagnosis

• Accepts withdrawal of all psychotropic medication

Exclusion Criteria:

• Extensive dissociative symptoms or current psychosis,

• Current suicidal risk,

• Extensive current substance or alcohol abuse, or

• Ongoing trauma

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Posttraumatic Stress Disorder
• Stress Disorders, Post-Traumatic
• Stress Disorders, Traumatic

Intervention

Behavioral:
• Imaginal exposure
7 individual sessions of imaginal exposure of trauma memories according to the prolonged exposure treatment manual
• Imagery rescripting
7 individual sessions of imagery rescripting of trauma memories according to the imagery rescripting and reprocessing therapy manual

Locations

Country	Name	City	State
Norway	Modum Bad	Vikersund	Buskerud

Sponsors (2)

Lead Sponsor	Collaborator
Modum Bad	University of Oslo

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	PTSD symptoms		pretreatment, weekly during treatment, posttreatment, followup	No
Secondary	General psychiatric symptoms		pretreatment, weekly during treatment, postttreatment, followup	No