Effects of Dietary Proteins on Postprandial Lipaemia and Incretin Responses in Obese Subjects

Postprandial Inflammation Clinical Trial

Official title:

Effects of Dietary Proteins on Postprandial Lipaemia and Incretin Responses in Obese Subjects

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00809874
• Other study ID #: CERN-PPL-JHJ
• Status: Completed
• Phase: N/A
• First received: December 16, 2008
• Last updated: November 9, 2009
• Start date: February 2008
• Est. completion date: December 2008

Study information

• Verified date: November 2009
• Source: Aarhus University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Denmark: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.

Hypothesis: Certain dietary proteins reduce the amount of fat circulating in the blood stream following a fat rich meal. The effect is dependant of both the quality and the quantity of protein ingested.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11
• Est. completion date: December 2008
• Est. primary completion date: December 2008
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 40 Years to 75 Years

Eligibility

Inclusion Criteria:

• BMI >30 kg/m2 & <45 kg/m2

Exclusion Criteria:

• Diabetes

• lipid lowering drugs

• Liver-, Kidney- and/or Heart Disease

• Serious Hypertension (160/110)

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Hyperlipidemias
• Inflammation
• Postprandial Incretins
• Postprandial Inflammation
• Postprandial Lipaemia

Intervention

Dietary Supplement:
• Casein

• Whey Isolate

• Whey Hydrolysate

• Alphalact-Albumin

Locations

Country	Name	City	State
Denmark	Department of Clinical Nutrion	Aarhus

Sponsors (4)

Lead Sponsor	Collaborator
Aarhus University Hospital	Arla Foods, Nordic Centre of Excellence, The Danish Obesity Research Centre

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Triglyceride		0h- 1h- 2h- 4h- 6h- 7h- 8h postprandial	No
Secondary	Incretins		0h -1h -2h -4h -6h -7h -8h Postprandial	No