Postoperative; Parotitis Clinical Trial
— GenderOpioidVerified date | December 2016 |
Source | Mansoura University |
Contact | n/a |
Is FDA regulated | No |
Health authority | Egypt: Ministry of Higher Education |
Study type | Interventional |
Opioids are widely used for pain relief after major abdominal surgeries[1]. Sex differences in the opioid analgesia have been reported and investigated in human subjects and animal models In this study, effects of sex difference on response to opioid analgesics after abdominal surgeries will be assessed regarding; analgesic duration (primary variable), frequency of analgesic requirement, total opioid consumption, Opioid related complications (respiratory depression, Nausea & vomiting, itching, over-sedation, delayed intestinal motility).
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | July 2017 |
Est. primary completion date | May 2017 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 45 Years |
Eligibility |
Inclusion Criteria: - ASA I and II Cases scheduled for elective intraabdominal surgeries Exclusion Criteria: - diabetes, - postmenopausal females, - laparoscopic surgery, - regional anesthesia emergency procedures, - sepsis, - hepatectomy, - Renal impairment, and - hepatic impairment, - mental and psychiatric disorders. |
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Mansoura University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | postoperative morphine consumption | 24 hours after surgery | Yes |