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Clinical Trial Summary

Vaginal hysterectomy is the preferred route of choice for women desiring hysterectomy to treat uterine pathology, including premalignant conditions and fibroids. Compared with an abdominal or a laparoscopic approach, VH has been associated with a shorter recovery time and faster return to daily activities. However, management of postoperative pain still remains challenging for patients undergoing VH. Duloxetine is a serotonin-norepinephrine reuptake inhibitor commonly prescribed for the treatment of major depression and anxiety. Duloxetine also has been used in the treatment of chronic pain conditions, such as osteoarthritis and musculoskeletal pain In contrast, studies examining its use to ameliorate acute postoperative pain are limited to a single trial.12 More importantly, it remains to be determined whether perioperative duloxetine can improve the global quality of recovery after surgery. The study included the hypothesis that perioperative duloxetine would ease postoperative recovery in patients undergoing VH, and the Quality of Recovery-15 questionnaire (QoR-15) was to be used for evaluation


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06429605
Study type Interventional
Source Erzincan Military Hospital
Contact Kemal Güngördük
Phone 05057465266
Email drkemalgungorduk@gmail.com
Status Not yet recruiting
Phase N/A
Start date May 20, 2024
Completion date January 15, 2025

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