External Oblique Intercostal Plane Block for Liver Transplantation Donors

Postoperative Pain Clinical Trial

Official title:

External Oblique Intercostal Plane Block for Postoperative Analgesia in Living Liver Donors

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05890079
• Other study ID #: anestezi2
• Status: Completed
• Phase: N/A
• Start date: May 8, 2023
• Est. completion date: January 17, 2024

Study information

• Verified date: May 2023
• Source: Istinye University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Postoperative pain management is one of the important factors to improve rehabilitation and enhance recovery. External oblique intercostal plane block may be used for abdominal wall analgesia to provide effective analgesia for abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block and subcostal transversus abdominis plane block in living liver donors.

Researchers will compare the external oblique intercostal plane block group with subcostal transversus abdominis plane block to see if the external oblique intercostal plane block is effective for postoperative analgesia in living liver donors.

Description:

Patients scheduled for living donor hepatectomy will be separated into 2 groups: Subcostal Transversus Abdominis Plane Block Group and External Oblique Intercostal Plane Block Group. Patients in Subcostal Transversus Abdominis Plane Block will be performed subcostal transversus plane block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Patients in External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 64
• Est. completion date: January 17, 2024
• Est. primary completion date: December 14, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Age between 18 and 75 years

• Patients with American Society of Anesthesiology (ASA) physical status I-II

• Patients scheduled for a living donor hepatectomy

Exclusion Criteria:

• Allergy to local anesthetics

• Coagulopathy

• Skin infection at the block area

• Advanced renal failure

• Chronic pain syndromes

• Alcohol or drug abuse

• Psychiatric disorders

Related Conditions & MeSH terms

• Donor
• Liver Transplantation
• Pain, Postoperative
• Postoperative Pain

Intervention

Other:
• Subcostal transversus abdominis plane block
External oblique intercostal plane block will be administered at the end of the surgery and after skin closure.
• External oblique intercostal plane block
External oblique intercostal plane block will be administered at the end of the surgery and after skin closure. .

Locations

Country	Name	City	State
Turkey	Istinye University Hospital	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Istinye University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Morphine consumption	The amount of morphine required by the patient and given by the device will be recorded for the first 24 hours.	Postoperative 24 hours
Secondary	Postoperative visual analog scale scores	Postoperative pain will be assessed using a visual analog scale (VAS) (from 0 = no pain to 10 = maximum possible pain) for the first 24 hours.	Postoperative 24 hours
Secondary	Rescue analgesic drug consumption	The amount of rescue analgesic in mg required by the patient will be recorded for the first 24 hours.	postoperative 24 hours
Secondary	Incidence of postoperative nausea and vomiting	Number of patients developing postoperative nausea and vomiting will be recorded for the first 24 hours	postoperative 24 hours