TAP Block vs CWI for Total Abdominal Hysterectomy, a RCT — WI-HYSTER  

Postoperative Pain Clinical Trial

Official title: Anestesia Generale + TAP Block vs Anestesia Generale + CWI Per Intervento di Isterectomia Totale Laparotomica. Trial Randomizzato Controllato.

Status Not yet recruiting

Clinical Trial Summary

This no-profit, monocentric, prospective randomized controlled trial, aims to demonstrate the non-inferiority of continuous wound infusion (CWI) when compared to transversus abdominis plane (TAP) block for postoperative pain control after total abdominal hysterectomy.

Clinical Trial Description

After signing the informed consent, patients will be enrolled and randomly allocated into either the study group (CWI) or the control group (TAP). Both groups will receive standard general anesthesia. At the end of the surgery, the CWI patients will receive a preperitoneal catheter in the surgical wound and CWI of ropivacaine 2 mg/ml, 5 ml/h for 24 hours; with the TAP block patients will receive a bilateral, standard lateral TAP block with 5 mg/ml ropivacaine 24 ml per side. All patients will receive multimodal analgesia with ketorolac 30 mg e.v. plus 90 mg/24h IV, paracetamol 1g plus 1g TID, dexamethasone 0,1 mg/kg IV preoperatively, oxycodone 5 mg per OS upon request. ;

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain

• NCT number: NCT05686382
• Study type: Interventional
• Source: Campus Bio-Medico University
• Contact: Fabio Costa, Dr.
• Phone: 3356526433
• Email: f.costa@policlinicocampus.it
• Status: Not yet recruiting
• Phase: N/A
• Start date: January 4, 2023
• Completion date: December 31, 2023