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Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery

Postoperative Pain Clinical Trial

Official title:
Association Between Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery: Randomized Clinical Trial, Placebo-controlled, Double-blind

Clinical Trial Summary

A randomized clinical trial will be performed in parallel, placebo controlled, triple-blind to evaluate the effectiveness of the association Bromelina and Horse-chestnut (titrated in escin) (Noflogo®, Mavenpharma s.r.l., Rome, Italy) in the management of post trauma-surgery following surgery periodontal and implant surgery.

Clinical Trial Description

At least 50 volunteers between the ages of 18 and 50, will be enlisted, with the need to perform one of the interventions described above and that fall within the criteria of inclusion. The study will be carried out in accordance with the Helsinki Declaration on In Vivo Studies and will be initiated with the approval of the Internal Review Board of the University of L'Aquila. The protocol follows the guidelines of the CONSORT Statement for parallel studies and will be recorded on the data base clinicaltrials.gov. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04657874
Study type Interventional
Source University of L'Aquila
Contact
Status Completed
Phase N/A
Start date December 1, 2020
Completion date May 27, 2021
View Details
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