Continuous Pectoral Nerve Block in Breast Cancer Surgery

Postoperative Pain Clinical Trial

Official title:

The Effect of Continuous Pectoral Nerve Block on Postoperative Analgesia Consumption in Breast Cancer Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04036370
• Other study ID #: 13/21
• Status: Completed
• Phase: N/A
• Start date: July 30, 2019
• Est. completion date: November 15, 2019

Study information

• Verified date: July 2019
• Source: Antalya Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of the study is to evaluate the effect of continuous pectoral nerve block on postoperative analgesia consumption in breast cancer surgery.

Description:

Pectoral nerve block has been developed as an alternative to thoracic paravertebral and/or thoracic epidural blocks in recent years. It is frequently applied for postoperative analgesia in breast cancer surgery.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 48
• Est. completion date: November 15, 2019
• Est. primary completion date: November 15, 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• American Society of Anesthesiology (ASA) I-II

• 18-65 years

• Body mass index (BMI) =40 kg/m2

• Elective breast cancer surgery

Exclusion Criteria:

• ASA =4

• under 18 years of age or over 65 years of age

• declining to give written informed consent

• history of allergy to the local anesthetics

• contraendications of peripheral block or local anesthetic infiltration (local infection, coagulopathy, etc)

• history of breast surgery

• treatment due to psychiatric disorder

• history of treatment for chronic pain

• history of nerve blocks in order to treat postoperative pain

Related Conditions & MeSH terms

• Breast Surgery
• Nerve Blocks
• Pain, Postoperative
• Postoperative Pain

Intervention

Procedure:
• PECS group
Pecs block performed using ultrasound guidance. Standard pain follow up and monitorization will be performed.

Other:
• Control group
Standard pain follow up and monitorization will be performed.

Locations

Country	Name	City	State
Turkey	Antalya Training and Research Hospital, Department of Anesthesiology and Reanimation	Antalya

Sponsors (1)

Lead Sponsor	Collaborator
Antalya Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

References & Publications (3)

Bashandy GM, Abbas DN. Pectoral nerves I and II blocks in multimodal analgesia for breast cancer surgery: a randomized clinical trial. Reg Anesth Pain Med. 2015 Jan-Feb;40(1):68-74. doi: 10.1097/AAP.0000000000000163. — View Citation

Blanco R, Fajardo M, Parras Maldonado T. Ultrasound description of Pecs II (modified Pecs I): a novel approach to breast surgery. Rev Esp Anestesiol Reanim. 2012 Nov;59(9):470-5. doi: 10.1016/j.redar.2012.07.003. Epub 2012 Aug 29. — View Citation

Blanco R, Parras Maldonado T. Reply to the article entitled "Ultrasound description of Pecs II (modified Pecs I): a novel approach to breast surgery". Reply of the authors. Rev Esp Anestesiol Reanim. 2013 May;60(5):296-7. doi: 10.1016/j.redar.2013.01.002. Epub 2013 Feb 27. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	analgesia consumption	postoperative 12 hours	12 hours
Secondary	analgesia consumption	intraoperative	during the surgery
Secondary	postoperative Numeric Rating Scale (NRS) score	postoperative pain assessment will be performed using NRS score (NRS 0=no pain, NRS 10= most severe possible). The NRS scores will be recorded at postoperative 0, 1, 3, 6, 9, 12 hours	0, 1, 3, 6, 9, 12 hours