Ultrasound Guided Anterior Quadratus Lumborum Block

Postoperative Pain Clinical Trial

Official title:

Ultrasound Guided Anterior Quadratus Lumborum Block for Postoperative Pain After Percutaneous Nephrolithotomy: Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03425162
• Other study ID #: BYIEAH
• Status: Completed
• Phase: N/A
• Start date: February 12, 2018
• Est. completion date: August 18, 2018

Study information

• Verified date: November 2018
• Source: Bursa Yüksek Ihtisas Education and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Percutaneous nephrolithotomy (PNL) is frequently used today for renal stones. percutaneous nephrolithotomy (PNL) procedure has become the treatment of choice for many patients with symptomatic renal stones . Patients undergoing PNL suffer from acute postoperative pain, despite a multimodal analgesic regime.

This is a randomised controlled trial efficacy of the anterior Quadratus Lumborum Block (QLB) in terms of analgesic efficacy in patients who undergo percutaneous nephrolithotomy.

Description:

Many analgesic procedures such as NSAID, opioid and regional anesthesia procedures are used as a part of multimodal analgesia for postoperative Percutaneous nephrolithotomy pain.

In this study we will use the ultrasound -guided anterior Quadratus Lumborum Block . Local anesthesic will be injected between quadratus lumborum muscle and psoas muscle with ultrasound.Analgesic effect of this block will be detected by using morphine consumption and visual analogue scale .

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: August 18, 2018
• Est. primary completion date: August 18, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• Patients who were in the American Society of Anesthesiologists (ASA) I-III class and underwent elective Percutaneous nephrolithotomy

Exclusion Criteria:

• Previous history of opioid use preoperatively,

• Allergy to local anesthetics,

• The presence of any systemic infection,

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain
• Ultrasound

Intervention

Drug:
• Morphine Sulfate
patient-controlled analgesia (PCA) morphine

Procedure:
• Group P
Group P:patient-controlled analgesia (PCA) morphine
• Group A
Group A:Ultrasound guided unilateral anterior Quadratus Lumborum block with 20 ml %0.25 Bupivacaine

Locations

Country	Name	City	State
Turkey	University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital	Bursa

Sponsors (1)

Lead Sponsor	Collaborator
Bursa Yüksek Ihtisas Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Visual Analog Scale	Visual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0= no pain, 10=intolerable pain)	Postoperative 24 hours
Secondary	morphine consumption	morphine consumption	Postoperative 24 hours
Secondary	side effect profile	side effect profile (Nausea and vomiting scale,Hypotension,Ramsay Sedation Scale); Nausea and vomiting scale (nausea-vomiting scale (NVS): 1. No nausea is present, 2. Mild nausea is present. 3. Severe nausea is present. 4. Vomiting is present) In case of a NVS score of >3, an anti-emetic drug was administered.; Hypotension; Ramsay Sedation Scale (Ramsay Sedation Scale (RSS) : 1. Anxiety, agitation are present; 2. Cooperated, awake; 3. Sedatized, response to commands; 4. Sleepy, immediately awoken by auditory stimulus or glabella tap; 5. Sleepy, deep response to auditory stimulus or glabella tap and 6. Sleepy, no response to auditory stimulus or glabella tap )	Postoperative 24 hours
Secondary	additional analgesic use	additional analgesic use	Postoperative 24 hours