Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery

Postoperative Pain Clinical Trial

— CDAAMIUVLS  

Official title:

Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03311737
• Other study ID #: zs20170511
• Status: Recruiting
• Phase: Phase 1
• First received: September 23, 2017
• Last updated: October 14, 2017
• Start date: September 19, 2017
• Est. completion date: March 31, 2018

Study information

• Verified date: September 2017
• Source: Shanghai Zhongshan Hospital
• Contact: yi li, Ph.D
• Phone: 13816836628
• Email: loulan_queen[@]163.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This is a single center, randomized, single blind study to compare the analgesic effect of different anesthesia and postoperative analgesic methods in uniportal VATS lung surgery.

Description:

Combining epidural with general anesthesia is regarded as the gold standard of general thoracic surgery. The uniportal VATS lung surgery have advantages of minimal invasive surgical incision, less postoperative pain, and so on. Whether general anesthesia can become an alternative method of combining epidural with general anesthesia in uniportal VATS lung surgery, investigators thus plan to make a comparison on intraoperative stress response, postoperative pain, immune function of patients，and hospital expenses.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: March 31, 2018
• Est. primary completion date: March 31, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Patients elective uniportal VATS lung surgery;

• BMI 18-30 kg/m2.

Exclusion Criteria:

• Patient refuse;

• ASA=3;

• Patients allergic to use anesthetics (propofol,rocuronium), patients with liver and/or kidney and/or mental dysfunction.

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain
• Single-incision Thoracoscopic Surgery

Intervention

Combination Product:
• general anesthesia
The investigators used general anesthesia preoperatively in uniportal VATS lung surgery
• epidural anesthesia
The investigators used general anesthesia combined with epidural anesthesia preoperatively in uniportal VATS lung surgery

Locations

Country	Name	City	State
China	Zhongshan Hospital	Shanghai	Shanghai

Sponsors (1)

Lead Sponsor	Collaborator
Shanghai Zhongshan Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	visual analogue scale(VAS)	This scale mainly reflects the patient's pain	1 year