Postoperative Pain Clinical Trial
Official title:
Comparison of the Postoperative Analgesia Effectiveness of Preemptive Intravenous Ibuprofen and Paracetamol in Patients Undergoing Laparoscopic Cholecystectomy
This study will evaluate two different analgesic regimen used for acute postoperative pain.
Laparoscopic cholecystectomy is a type of surgery that causes moderate postoperative pain.
Paracetamol and non-steroid anti-inflammatory analgesics plus opioids are the mainstay
treatment options of the moderate postoperative pain. These drugs are the most common used
analgesics to ameliorate this type of pain and to reduce the consumption of opioids and their
side effects.
Ibuprofen is a well-known anti-inflammatory drug and has been used as an oral formula for a
long time. Few studies using its new intravenous formula had been conducted to evaluate its
effectiveness for mixed type of surgeries . However, its intravenous formula has not been
studied for laparoscopic cholecystectomy. Therefore, this study will compare the effects of
postoperative analgesic potencies of preemptive intravenous paracetamol and ibuprofen in
patients undergoing laparoscopic cholecystectomy.
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