Postoperative Pain Clinical Trial
Official title:
Infra-orbital Nerve Block for Post Operative Analgesia in Young Children Undergoing Pediatric Cleft Lip Surgery.
this study will be undertaken to evaluate the safety and analgesic efficacy of adding ketamine to bupivacaine in bilateral infra-orbital nerve block for relief of pain postoperatively following repair of cleft lip in children less than two years of age.
Oro-facial clefts are the most prevalent craniofacial birth defects and the second most
common birth anomaly, second only to clubfoot [Strong & Buckmiller 2001]. Cleft lip surgery
is associated with appreciable postoperative pain in children Alleviation of postoperative
pain is important in these patients. The fear of respiratory depression using opioids has
renewed the interest in regional anesthesia to provide safe and effective postoperative
analgesia. Infra-orbital nerve block has been advocated as a suitable local analgesic
technique for cleft lip surgery and superficial surgery on the mid face [Morton 2004, Takmaz
et al. 2009, Rajesh et al. 2011, Jindal et al. 2011].The infra-orbital nerve supplies the
upper lip, lower eyelid, and adjacent skin of the cheek and nose. Unilateral or bilateral
infra-orbital nerve block has been performed with a very high success rate.
The investigators designed this study to evaluate the safety and analgesic efficacy of
adding ketamine to bupivacaine in bilateral infra-orbital nerve block for relief of pain
postoperatively following repair of cleft lip in children less than two years of age.
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