Postoperative Pain Clinical Trial
Official title:
Intravenous Lornoxicam is More Effective Than Paracetamol as a Supplemental Analgesic After Lower Abdominal Surgery; A Randomized Controlled Trial
Background: The aim of this prospective, randomized, double-blind study is to determine the
most effective supplemental analgesic, paracetamol or lornoxicam for postoperative pain
relief after lower abdominal surgery.
Methods: Sixty patients scheduled for lower abdominal surgery under general anesthesia were
randomly allocated to receive either isotonic saline (Control group), intravenous
paracetamol 1 g every 6 h (Paracetamol group) or lornoxicam 16 mg then 8 mg after 12 h
(Lornoxicam group). Additionally pain was treated postoperatively using morphine
patient-controlled analgesia. Postoperative pain scores measured by the verbal pain score
(VPS), morphine consumption and the incidence of side effects were measured at 1, 2, 4, 8,
12 and 24 hours postoperatively.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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