Management of Postoperative Pain After Total Knee Replacement.

Status Completed

Clinical Trial Summary

The purpose of this study is to compare two methods of postoperative pain management in patients undergoing total knee replacement.

Clinical Trial Description

Patients undergoing total knee replacement will be assigned at random to receive one of two methods of postoperative pain management. Patients assigned to nerve block will receive regional anesthetic nerve block using an indwelling femoral nerve catheter and a single shot sciatic nerve block. Patients assigned to periarticular injection will receive periarticular local injection into the periarticular soft tissues at the time of knee replacement using a combination of ropivacaine, epinephrine, ketorolac, and morphine sulphate. Additionally, all patients will be given a standardized combination of oral analgesic medications preoperatively and postoperatively. All patients will receive a posterior stabilized total knee replacement through an medial parapatellar approach. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01163214
Study type	Interventional
Source	Mayo Clinic
Contact
Status	Completed
Phase	Phase 4
Start date	July 2010
Completion date	June 2013

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