Postoperative Pain Clinical Trial
Official title:
Phase 4: A Comparison of Intravenous Administration of Morphine vs. Oxycodone for Postoperative Pain Management Following Laparoscopic Hysterectomy or Myomectomy
The purpose of this study is to determine whether oxycodone provides better analgesia compared to morphine after laparoscopic hysterectomy or myomectomy.
Status | Completed |
Enrollment | 90 |
Est. completion date | June 2008 |
Est. primary completion date | June 2008 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - Patients (American Society of Anaesthesiologists (ASA) I, II and III) due for elective, laparoscopic, non-malignant gynaecologic surgery: Hysterectomy or myomectomy. - Written informed consent. - Age: 18 to 70 years. Exclusion Criteria: - Patients having used non-steroidal anti-inflammatory drugs (NSAIDs) the last 24 hours. - Sensitivity towards the study drugs. - Cardiovascular risk conditions: Heart failure, unstable hypertension, coronary artery disease. - Patients using opioids, steroids or anti-emetic drugs. - Serious mental disease. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Norway | Ullevaal University Hospital | Oslo |
Lead Sponsor | Collaborator |
---|---|
Ullevaal University Hospital | University of Oslo |
Norway,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Dosage relation between oxycodone and morphine. Pain score (VAS). Adverse effects. | Within the first postoperative day (24 hours). |
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