Perioperative Multimodal Analgesia Protocol for Supratentorial Craniotomy

Status Not yet recruiting

Clinical Trial Summary

Supratentorial craniotomy is one of the most common neurosurgical procedures, with severe perioperative pain. Inadequate perioperative pain relief has been associated with increased blood pressure and intracranial pressure, favoring bleeding and cerebral cerebral hypoperfusion. The ideal analgesia for neurosurgery requires complete pain relief, eliminates the side effects of opioid drugs and no influence for neurological function. Previous studies have proposed a multimodal analgesic strategy, combining analgesics and local anaesthesia, it is expected to achieve the above benefits.

Clinical Trial Description

The trial has been designed to analyze the efficacy of local analgesic techniques and dexmedetomidine in the treatment of postoperative acute pain in craniotomy. This randomized clinical trial aims to enroll 2000 patients, which will be randomized to one of 4 groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06406829
Study type	Interventional
Source	Beijing Tiantan Hospital
Contact	Yuming Peng, Dr
Phone	8610-59976658
Email	florapym766@163.com
Status	Not yet recruiting
Phase	N/A
Start date	June 1, 2024
Completion date	December 31, 2026

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