Comparison of the Effects of Perineural Dexamethasone and Systemic Dexamethasone in PENG Block

Postoperative Pain Clinical Trial

Official title: Comparison of the Effects of Dexamethasone Administered Perinuerally and Dexamethasone Administered Systemically in PENG Block in Patients Operated for Femoral Neck Fracture

Status Active, not recruiting

Clinical Trial Summary

Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block targets the hip capsule. The aim of this study is to investigate and compare the perioperative analgesic efficacy of PENG blocks applied investigation of the effect of perinuerally and systemic dexamethasone on pain scores in the first 24 hours of PENG block in patients undergoing hip fracture surgery under spinal anesthesia.

Clinical Trial Description

Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block targets the hip capsule. The aim of this study is to investigate and compare the perioperative analgesic efficacy of PENG blocks applied investigation of the effect of perinuerally and systemic dexamethasone on pain scores in the first 24 hours of PENG block in patients undergoing hip fracture surgery under spinal anesthesia. 44 ASA II-IV patients between 50-80 years of age who will be operated for femoral neck fractures will be included in the study. PENG block is routinely used in our clinic to provide postoperative analgesia in hip surgery. Depending on the comorbid conditions of the patients, dexamethasone may be added as an adjuvant agent to improve the quality of the block. We aimed to observe the systemic and perinuerally effects of dexamethasone used in PENG block in patients operated for femoral neck fracture in our clinic. In this observational and prospective study, patients operated for femoral neck fracture and treated with PENG block will be analyzed in the postoperative period. Pain scores, degree of nausea and vomiting, recovery time of sensory and motor block, and blood glucose levels in the first 24 hours will be recorded in patients who received dexamethasone perinuerally and in patients who received systemic dexamethasone intravenously. In addition, the time to first analgesic requirement, mobilization time and hospital stay of the two groups will also be recorded. The anesthesiologist performing the block will not participate in the pain monitoring of the patients. Postoperative pain assessment and data collection will be performed by another anesthesiologist blinded to the study. For the quality and standardization of the block, the block will be performed by an experienced anesthesiologist who has performed the block successfully and without complications at least 20 times before. ;

Related Conditions & MeSH terms

• Acute Pain
• Hip Fractures
• Pain, Acute
• Postoperative Pain

• NCT number: NCT06242028
• Study type: Observational
• Source: Ondokuz Mayis University
• Status: Active, not recruiting
• Start date: December 27, 2023
• Completion date: June 27, 2024