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Postoperative Pain clinical trials

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NCT ID: NCT01261637 Completed - Postoperative Pain Clinical Trials

Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery

Start date: July 2009
Phase: Phase 4
Study type: Interventional

This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using ropivacaine have better pain relief and a better quality of recovery than women who don't have the additional TAP block. Maximizing pain relief using ultrasound guided TAP blocks in addition to neuraxial opioids, NSAIDs, and acetaminophen may improve acute pain outcomes, reduce adverse side effects, and potentially reduce chronic pain.

NCT ID: NCT01258413 Completed - Postoperative Pain Clinical Trials

Laparoscopic vs Abdominal Radical Hysterectomy In Patients With Early Cervical Cancer

Start date: November 1999
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether laparoscopic radical hysterectomy for early cervical cancer will has decreased postoperative pain intensity compared to abdominal radical hysterectomy with similar postoperative complications and survival rates.

NCT ID: NCT01249872 Completed - Postoperative Pain Clinical Trials

Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens

Start date: January 2010
Phase: Phase 2/Phase 3
Study type: Interventional

Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are available concerning the use of thoracic epidural patient-controlled analgesia regarding the use of levobupivacaine combined with morphine in morbidly obese patients. The investigators' aim in this prospective, randomized, double-blinded study was to compare the analgesic effectiveness, the dose requirements and side effects of thoracic epidural patient controlled analgesia 0.1% and 0.2% levobupivacaine combined with a continuous epidural administration of morphine, with or without a loading dose, after open gastric bypass for morbid obesity.

NCT ID: NCT01224145 Completed - Postoperative Pain Clinical Trials

Assess the Feasibility and Efficacy of the CollaRx® Bupivacaine Implant Laparoscopic Inguinal or Umbilical Herniorrhaphy

Start date: March 22, 2011
Phase: Phase 2
Study type: Interventional

This study will assess pain intensity for the first 72 hrs after aggravated movement (cough) following Laparoscopic Inguinal or Umbilical Herniorrhaphy.

NCT ID: NCT01220024 Completed - Postoperative Pain Clinical Trials

Safety and Efficacy of CollaRx® Bupivacaine Implant in Men After Open Laparotomy Herniorrhaphy

Start date: December 2, 2010
Phase: Phase 2
Study type: Interventional

This study will assess pain intensity for the first 72 hrs after after aggravated movement (cough)following open laparotomy inguinal herniorrhaphy in patient who receive either the CollaRx Bupivacaine implant or a plain collagen sponge.

NCT ID: NCT01206608 Completed - Postoperative Pain Clinical Trials

Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects Undergoing Augmentation Mammoplasty

Start date: March 2008
Phase: Phase 2
Study type: Interventional

The primary objective of this study was to demonstrate the superiority of SKY0402 over conventional, commercially-available bupivacaine HCl with respect to the duration of the analgesic effect achieved by a single local administration of the study drug.

NCT ID: NCT01206595 Completed - Postoperative Pain Clinical Trials

Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block in Subjects Undergoing Bunionectomy

Start date: March 2005
Phase: Phase 2
Study type: Interventional

The primary objective of this study was to determine the appropriate dose of SKY0402 administered as a nerve block for the management of postoperative pain following bunionectomy.

NCT ID: NCT01204892 Completed - Postoperative Pain Clinical Trials

Pain After Laparoscopic Cholecystectomy With Bilateral Tranversus Abdominis Plane (TAP) Block Versus Local Anesthetic Infiltration

Start date: September 2010
Phase: N/A
Study type: Interventional

The purpose if to find out if analgesia with bilateral ultrasound-guided Tranversus Abdominis Plane (TAP) block with Ropivacaine 0.5% is better than analgesia with local infiltration of trochar sites with Ropivacaine 0.5% in patients undergoing laparoscopic cholecystectomy. Our hypothesis is that in laparoscopic cholecystectomy, bilateral TAP blocks will reduce postoperative pain scores when compared to conventional postoperative pain control with local infiltration of trochar insertion sites.

NCT ID: NCT01199406 Completed - Postoperative Pain Clinical Trials

Pain Reduction After Cholecystectomy

INTENSE
Start date: July 2009
Phase: Phase 4
Study type: Interventional

To determine the effect of combined intracutaneous infiltration and intraperitoneal instillation of 80 mL 0,125% levobupivacaine prior to the start of laparoscopic cholecystectomy on abdominal pain up to 24 hours after surgery.

NCT ID: NCT01191593 Completed - Postoperative Pain Clinical Trials

The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee Arthroplasty

Start date: September 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing pain and morphine consumption after revision knee arthroplasty.