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Postoperative Pain clinical trials

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NCT ID: NCT04710069 Completed - Postoperative Pain Clinical Trials

Postoperative Opt-In Narcotic Treatment Study

POINT
Start date: June 26, 2020
Phase: N/A
Study type: Interventional

pills go unused, generating waste and leaving an opportunity for misuse and abuse. In a recent study, researchers let patients choose what medications to go home with after surgery. After their thyroid or parathyroid surgery, 96% of patients declined narcotic pain medication. They preferred to manage their pain with acetaminophen instead. Giving patients counseling and empowering them to choose significantly reduces the amount of opioids prescribed and wasted. The aim of our study is to compare a similar "opt-in" protocol for narcotics to usual care (where patients are routinely discharged with opioids). We would elaborate upon the aforementioned study by studying patient pain scores on a more granular level once they return home. Our study will be designed as a randomized, controlled trial. When adult patients consent for a thyroid or parathyroid surgery, they will be asked to participate in the study. Patients who are currently using narcotics would be excluded. We would then randomize participants to the "opt-in" protocol versus being provided with a standard opioid prescription after surgery. Patients in the opt-in protocol will be recommended a pain treatment regimen with over-the-counter medications, such as acetaminophen or ibuprofen. These patients will be reassured that if their pain is uncontrolled after discharge, a narcotic prescription will be called in to their pharmacy if requested. We will assess patient pain scores and medication use in the recovery area using the electronic medical record. We will collect data on patient pain scores and medication use after discharge on a daily basis via phone call or electronically transmitted survey. We will also evaluate patients at the time of their follow-up visits. Any patient phone calls will be routed to study personnel who will fill narcotic prescription requests if requested. Finally, among patients who do receive an opioid prescription, we will track their opioid consumption.

NCT ID: NCT04709250 Completed - Postoperative Pain Clinical Trials

Evaluating the Analgesic Efficacy of Combined Individual Nerve Block in Comparison to Interscalene Nerve Block

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Patients undergoing total shoulder arthroscopic adhesiolysis may experience severe postoperative pain. Inadequate pain management can result in unfavourable hospital outcomes and the development of persistent neuropathic manifestation the aim of the study is to compare both ultrasound techniques (combined individual nerve block to interscalene nerve block) as regards the postoperative analgesic effect and shoulder range of movement.

NCT ID: NCT04709211 Completed - Postoperative Pain Clinical Trials

Fascia Iliaca Compartment Block Versus Anterior Quadratus Lumborum Block

Start date: January 10, 2021
Phase: N/A
Study type: Interventional

Fractures of the femur are common orthopaedic emergency especially in the geriatric population and central neuraxial blocks are the preferred technique for providing anaesthesia. However, limb immobility and extreme pain are the deterrents for ideal positioning for these procedures. postoperative pain is a nightmare so adequate analgesia has been advocated to reduce the pain. in this study, Facia Iliaca compartment block will be compared to anterior Quadratus lumborum block, both will be done Ultrasound-guided using Bupivacain0.25% for postoperative analgesia at the end of the surgery.

NCT ID: NCT04703257 Completed - Surgery Clinical Trials

Evaluation of the Added Value of Metamizole to Standard Postoperative Treatment After Ambulant Shoulder Surgery

Metamizole003
Start date: February 26, 2021
Phase: N/A
Study type: Interventional

This study aims to investigate if the combination of metamizole and paracetamol is superior in reducing post-operative pain on day 1 after ambulatory shoulder surgery where the use of NSAIDs is prohibited compared to paracetamol treatment. Therefore, a monocenter, prospective, double-blind, randomized controlled superiority trial will be designed to investigate the superiority of the combination of metamizole and paracetamol compared to paracetamol treatment in patients undergoing arthroscopic shoulder surgery with tendon repair.

NCT ID: NCT04699084 Completed - Postoperative Pain Clinical Trials

The Evaluation of Mozart Music on Pain and Respiratory Rate After Thyroidectomy

Start date: February 20, 2018
Phase: N/A
Study type: Interventional

To investigate the effect of Mozart music on postoperative pain and physiological parameters in patients after total thyroidectomy.

NCT ID: NCT04697420 Completed - Postoperative Pain Clinical Trials

Transversus Abdominis Plane Block Versus Paravertebral Block for Post Operative Pain Relief in Open Renal Surgeries

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Pain relief after renal surgeries is essential as it may lead to reduction in the incidence of many post operative complications . There are a lot of regional anesthetic techniques to provide analgesia postoperatively as paravertebral block (PVB) and transversus abdominis plane (TAP) block. TAP block has been used to provide postoperative analgesia in a lot of abdominal surgeries including upper abdominal surgeries.It is safer technique than PVB, but the effectiveness of TAP block is unknown in comparison with PVB in post operative analgesia after renal surgeries .

NCT ID: NCT04697329 Completed - Postoperative Pain Clinical Trials

Local Infiltration With Levobupivacaine During Laparoscopic Cholecystectomy

Start date: December 3, 2020
Phase: Phase 4
Study type: Interventional

Randomized controlled trial on laparoscopic cholecystectomy. Interventional group: preincisional infiltration with levobupivacaine. Control group: no local infiltration. Postoperative pain with numeric rating scale is registered, besides other parameters like heart rate, blood pressure, rescue analgesia requirements, nausea and vomiting, etc.

NCT ID: NCT04696445 Completed - Postoperative Pain Clinical Trials

Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery

Start date: October 1, 2020
Phase:
Study type: Observational

- Single centre observational cohort study. - 20 older patients undergoing cardiac surgery who receive standard of care pain treatment. - Postoperative ICU: blood sampling to determine morphine and metabolite (M3G, M6G, noroxycodone and oxymorphone) pharmacokinetics - After ICU discharge on general ward: blood sampling to determine morphine, oxycodone and metabolite (M3G, M6G, noroxycodone and oxymorphone) pharmacokinetics - During study monitoring of pain scores, total opioid consumption, side effects (e.g. nausea, vomiting, pruritus), sedation and delirium scores.

NCT ID: NCT04690491 Completed - Postoperative Pain Clinical Trials

Mü-opioid Receptor Level and Postoperative Pain in Patients With Gynecological Laparoscopy

Start date: May 15, 2020
Phase:
Study type: Observational [Patient Registry]

The hypothesis that gonadal hormones may affect the perception of pain is an interesting research area. This prospective observational study will undergo elective laparoscopic gynecological surgery to 18-65 years, is planned to participate in ASA 1-3, 60 volunteer patients. Patients who have known psychiatric disease and drug-users, an important cardiovascular or central nervous system disease, patients with pain syndromes or routinely using opioid, are non-irregular and predictable cycles of menstrual cycles and very urgent patients will not be included in the study. In our study, we aimed to determine the relationship between menstrual cyclus phases (follicular and luteal) of menstrual cyclus phases (follicular and luteal) in patients to undergo gynecological laparoscopic operation and the relationship between postoperative pain and opioid analgesic consumption.

NCT ID: NCT04689581 Completed - Postoperative Pain Clinical Trials

Comparison of Bi-level Erector Spine Plane Block and Combined Pectoral I-II Block in Breast Surgery

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

In this study, we compared ultrasound-guided modified pectoral nerve (PECS) block and bi level erector spinae plane (ESP) block on postoperative analgesic effect in breast surgery.