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Postoperative Pain clinical trials

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NCT ID: NCT00799175 Completed - Postoperative Pain Clinical Trials

Local Infiltration Analgesia Following Total Knee Arthroplasty

RAK-total
Start date: April 2007
Phase: N/A
Study type: Interventional

The primary aim of this study is to evaluate if intra- and postoperative administration of ropivacaine, ketorolac and epinephrine into the operating field would affect morphine consumption. Secondary end-points are hospital stay, pain intensity and side effects. In an attempt to assess the safety of this technique, knee function and patient satisfaction scores are assessed up to 3 months after surgery.

NCT ID: NCT00799162 Recruiting - Postoperative Pain Clinical Trials

Prediction of Post-Cesarean Section Pain

PPCSP
Start date: November 2008
Phase: N/A
Study type: Observational

The purpose of this study is to determine if dynamic psychophysical testing along with genetic screening will allow to identify pre-operatively women who will suffer severe acute pain post-operatively and the subset who may experience chronic pain following cesarean section.

NCT ID: NCT00793910 Completed - Postoperative Pain Clinical Trials

Oral Gabapentin Versus Placebo for Treatment of Postoperative Pain Following Photorefractive Keratectomy

Start date: July 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effectiveness of an oral medication called gabapentin in reducing pain after Photorefractive Keratectomy (PRK) eye surgery and to assess the frequency of use of rescue medication interventions, defined as non-steroidal anti-inflammatory (NSAID) eye drops and oral narcotic medication.

NCT ID: NCT00790829 Terminated - Postoperative Pain Clinical Trials

Preemptive Use of the Nicotine Patch for Postoperative Pain Relief After Open Abdominal Surgery

Start date: August 2007
Phase: N/A
Study type: Interventional

The efficacy of a low dose nicotine patch of seven milligrams placed before surgery and its effect on decreasing pain after surgery is the main purpose of the study.

NCT ID: NCT00790179 Completed - Postoperative Pain Clinical Trials

Continuous Lumbar Plexus Block for Postoperative Pain Control After Total Hip Arthroplasty

Start date: January 2003
Phase: N/A
Study type: Interventional

Continuous lumbar plexus and femoral blocks have been demonstrated to provide effective postoperative analgesia of the lower extremity following total joint arthroplasty. The purpose of this study was to compare these two techniques when used with intravenous patient-controlled analgesia and the use of patient-controlled analgesia alone for postoperative pain management following unilateral total hip arthroplasty.

NCT ID: NCT00785382 Completed - Postoperative Pain Clinical Trials

Pregabalin for Postoperative Pain in Women Undergoing Breast Cancer Surgery

Start date: January 2009
Phase: Phase 4
Study type: Interventional

We hypothesize that pregabalin will decrease postoperative pain, as measured by the surrogate markers postoperative pain rating scores and postoperative opioid consumption while improving the quality of recovery following breast cancer surgery compared to placebo. The primary outcome will be postoperative pain, measured by a NRS and the quality of recovery score (QoR) in the first 24h postoperative period. Do women undergoing breast cancer surgery with general anesthesia and receiving pregabalin prior to their surgery and 12 hours later have lower NRS and a greater QoR score in the first 24 hours after their surgery than those women who received placebo?

NCT ID: NCT00781131 Completed - Postoperative Pain Clinical Trials

Trial of Pregabalin for Post-operative Pain in Women Undergoing Abdominal Hysterectomy

Start date: May 2008
Phase: Phase 4
Study type: Interventional

We hypothesize that pregabalin will decrease post-operative pain scores and opioid use following abdominal hysterectomy compared to placebo. This study has been designed to determine if after an abdominal hysterectomy, the addition of pregabalin to their peri-operative analgesia regimen will demonstrate superior analgesia compared to placebo in terms of lower pain scores and reduced usage of opioids. The primary outcome will be post-operative pain, measured by total opioid consumption. Do women undergoing an abdominal hysterectomy with general anesthesia and receiving pregabalin prior to their surgery and 12 hours later have lower opioid consumption in the first 24 hours after their surgery than those women who received placebo?

NCT ID: NCT00764283 Completed - Postoperative Pain Clinical Trials

The Prevention of Postoperative Epidural Catheter Migration: a Comparison of Three Types of Dressing

Start date: November 2008
Phase: N/A
Study type: Interventional

Three types of dressing will be compared to prevent postoperative epidural catheter migration. Patients will be randomised to have a Tegaderm dressing, an Epi-fix dressing or a Lockit-Plus dressing to secure the epidural catheter for postoperative analgesia. The length of the epidural catheter visible at the patient's skin surface will be recorded after insertion and every day until removal. The integrity of the dressing and problems with analgesia will also be recorded.

NCT ID: NCT00754806 Completed - Postoperative Pain Clinical Trials

Prospective Randomized Comparison of Clinical Results of Hand Assisted Laparoscopic Splenectomies and Open Splenectomies

Start date: February 2007
Phase: N/A
Study type: Observational

ABSTRACT Background: Although there are some comparative studies between laparoscopy and hand-assisted laparoscopic splenectomy (HALS) in splenomegaly cases, there is no study of the differences between HALS and open splenectomy (OS). Our aim was to compare the HALS and OS techniques in splenomegaly cases. Methods: This prospective study included 27 patients undergoing splenectomy for splenic disorders at the Department of General Surgery, Istanbul Medical Faculty between February 2007 and October 2007. OS was performed on 14 patients, and HALS was performed in the other 13 patients. Key words: HALS, open splenectomy, splenomegaly

NCT ID: NCT00746720 Terminated - Pain Clinical Trials

Modulation of the Surgical Inflammatory Response by Etoricoxib

Start date: May 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the hypothesis that orally administered etoricoxib (COX-2) modulates prostaglandin and cytokine synthesis in the central nervous system (CNS) and in the periphery in surgical patients and thus reduces pain and suffering.