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Postoperative Hemorrhage clinical trials

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NCT ID: NCT06308003 Recruiting - Hip Arthropathy Clinical Trials

Effect of Surgical Approach on Postoperative Bleeding in Patien Arthroplasty

Start date: February 13, 2023
Phase:
Study type: Observational

The study is, in accordance with current legislation, definable as monocentric Prospective Observational. The primary outcome will be blood loss calculated on the basis of hemoglobin (Hb) on the third postoperative day. adult patients who will undergo surgery of hip arthroplasty. Patients will undergo: Preoperative T0: clinical visit/medical history, completion of the VAS questionnaire, Blood sampling to assess hemoglobin values Operative T1: hip arthroplasty surgery using one of the surgical approaches routinely used within our Institute T2 - Postoperative at 1 day from T1: VAS questionnaire, evaluation of any Adverse events T3 - Postoperative at 3 days from T1: blood loss based on the values of hemoglobin (Hb), assessment of any adverse events, and VAS questionnaire T4- Post operative at 45 days +/- 10 days from T1: evaluation of any events adverse, follow-up visit.

NCT ID: NCT06049160 Recruiting - Clinical trials for Blood Loss, Surgical

Comparative Study Between Preoperative and Postoperative Rectal Misoprostol

Start date: August 31, 2023
Phase: N/A
Study type: Interventional

Cesarean delivery (CD) is the most common major surgical procedure undergone by women around the world. Over the past two decades, there has been a witnessed increase in rates of caesarean deliveries, which continues to rise, achieving 30% in resource-rich countries and exceeding 60% in resource-limited countries. According to a Lancet report 2014, Egypt is one of the countries with the highest rates of caesarean delivery, in which the rate had reached 55.5%. The rate is almost double to three times the ideal rate of 10%-15%

NCT ID: NCT05994989 Recruiting - Clinical trials for Postoperative Hemorrhage

Two Different Tranexamic Acid Regimens in Coronary Artery Bypass Surgery

Start date: August 14, 2023
Phase:
Study type: Observational

The primary aim of this study is to observe the effects of two different methods of administering tranexamic acid (i.v. bolus and i.v. infusion) routinely used intraoperatively in cardiovascular surgery, on patients' postoperative bleeding amounts. According to the hypothesis established in this study, it is anticipated that administering tranexamic acid as an i.v. bolus dose followed by an 8-hour continuous infusion will result in a more stable blood level compared to the sole i.v. bolus application, thereby being more effective in influencing postoperative bleeding levels. The study has been designed as a prospective observational research. The outcomes of two different tranexamic acid protocols applied during cardiovascular surgical procedures will be compared. The first group will consist of patients who receive a 10 mg/kg i.v. bolus of tranexamic acid after anesthesia induction, followed by an 8-hour i.v. tranexamic acid infusion at a dose of 2 mg/kg/hour. Group 2 will consist of patients who receive three doses of tranexamic acid, 10 mg/kg i.v. bolus after anesthesia induction, in the pump, and after protamine sulfate administration. The cases collected over a period of 6 months will be divided into two groups and compared in terms of intraoperative and postoperative bleeding levels, as well as their need for blood products.

NCT ID: NCT05774717 Recruiting - Surgery Clinical Trials

Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis

Start date: April 1, 2023
Phase: Phase 1
Study type: Interventional

This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at Vanderbilt. Outcomes will include intra- and post-operative bleeding and postoperative bruising and swelling.

NCT ID: NCT05427513 Recruiting - Clinical trials for Blood Loss, Surgical

Efficacy of Tranexamic Acid in Preventing Post Operative Blood Loss in Bone Sarcoma Patient

Start date: April 6, 2022
Phase: Early Phase 1
Study type: Interventional

investigator will see the efficacy of tranexamic acid in limb salvage surgery patients which will prevent blood loss and help in conservation of blood products.

NCT ID: NCT05316649 Recruiting - Clinical trials for Postoperative Complications

Blood Loss Quantification During Major Abdominal Surgery

Start date: May 1, 2021
Phase:
Study type: Observational

Blood loss quantification during surgery remains unreliable and inaccurate. The purpose of the study is compare several methods of blood loss quantification in real surgical settings and to analyze the effect of blood loss on postoperative complications.

NCT ID: NCT05206799 Recruiting - Child Clinical Trials

The CMCPCTH Research in Chinese Children

Start date: January 15, 2022
Phase:
Study type: Observational

To obtain hemorrhage rate after coblation tonsillectomy, and to investigate risk factors of hemorrhage after coblation tonsillectomy in children.

NCT ID: NCT05077124 Recruiting - Clinical trials for Blood Loss, Surgical

Safe and Timely Antithrombotic Removal (STAR) Registry

Start date: September 30, 2021
Phase:
Study type: Observational

This registry will capture real-world clinical use patterns and associated clinical outcomes with the use of CytoSorb for the removal of antithrombotic agents.

NCT ID: NCT05047133 Recruiting - Clinical trials for Postoperative Blood Loss

Effect of Early Administration of TXA in Adult Hip Fractures

Start date: September 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This is a prospective clinical study designed to assess blood loss in intracapsular and extracapsular hip fractures undergoing operative fixation at a Level II trauma center. It is well established in the orthopedic literature that tranexamic acid (TXA) decreases blood loss and need for postoperative blood transfusion in hip fracture patients as well as total joint arthroplasty patients. A typical dosing pattern, and the dosing pattern employed at our institution, is 1 gram IV infused prior to incision followed by 1 gram IV infused at the time of wound closure.

NCT ID: NCT04855877 Recruiting - Clinical trials for Anterior Cruciate Ligament Rupture

Oral Administration of Tranexamic Acid in Anterior Cruciate Ligament Surgery Reduce Postoperative Haemarthrosis

Start date: July 6, 2021
Phase: Phase 4
Study type: Interventional

To find superiority relationship between oral and intravenous administration of tranexamic acid on peroperative and postoperative blood loss, haemarthrosis prevalence and improvement functional prognosis in anterior cruciate ligament arthroscopy.