Postoperative Delirium Clinical Trial
Official title:
Perioperative Cytokines, Postoperative Delirium and Health Status in Older People Undergoing Hip Fracture Surgery - a Pilot Study
NCT number | NCT05096507 |
Other study ID # | 21052 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | June 6, 2022 |
Est. completion date | July 31, 2023 |
An investigation of the change in inflammation marker levels across hip fracture surgery and an exploration of any association with change in self reported health status and incidence of postoperative delirium
Status | Recruiting |
Enrollment | 60 |
Est. completion date | July 31, 2023 |
Est. primary completion date | May 30, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 65 Years and older |
Eligibility | Inclusion Criteria: - Age = 65 years old - Admitted for primary hip fracture surgery Exclusion Criteria: - Preoperative cognitive impairment - History of neurosurgery, neurologic diseases or head trauma - Current systemic bacterial or viral infection - Complex or multiple injuries |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Queen's Medical Centre | Nottingham |
Lead Sponsor | Collaborator |
---|---|
University of Nottingham |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Cytokine dynamics | Difference preoperative serum cytokine levels and postoperative serum cytokine levels in pg/mL. | 2 days | |
Primary | Incidence of postoperative delirium | Assessment for presence or absence of delirium during the post operative period. | 5 days | |
Secondary | Self reported health related quality of Life | Assessed preoperatively and again at approximately 120 days after surgery using the EuroQol Five Dimension Five level (EQ-5D-5L) tool. The tool assesses on five aspects of health (Dimensions) and each dimension has five possible levels. The tool also has a visual analogue scale ranging from 0 (poorest) to 100 (best health) | 120 days |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03606941 -
Effect of Electroacupuncture on the Incidence of Postoperative Delirium in Elderly Patients Undergoing the Major Surgery
|
N/A | |
Recruiting |
NCT05990790 -
The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium
|
Phase 4 | |
Completed |
NCT03950440 -
Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
|
||
Terminated |
NCT03337282 -
Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
|
||
Completed |
NCT02585128 -
Predictors of Postoperative Delirium After Transcatheter Aortic Valve Implantation
|
N/A | |
Recruiting |
NCT02227225 -
Factors Affecting the Incidence of Postoperative Delirium in Frail Elderly
|
N/A | |
Recruiting |
NCT01934049 -
Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
|
Phase 4 | |
Terminated |
NCT00455143 -
Cognitive Protection - Dexmedetomidine and Cognitive Reserve
|
Phase 4 | |
Recruiting |
NCT05010148 -
A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain
|
Phase 3 | |
Completed |
NCT06178835 -
EPO for Postop Delirium in Elderly Patients
|
Phase 4 | |
Recruiting |
NCT05992506 -
Electroencephalographic Biomarker to Predict Postoperative Delirium
|
||
Recruiting |
NCT03839784 -
Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
|
||
Completed |
NCT04154176 -
Validation of the Greek Version of the Confusion Assessment Method Diagnostic Algorithm (CAM) and the Nursing Delirium Screening Scale (Nu-DESC) and Their Inter-rater Reliablity
|
||
Not yet recruiting |
NCT06375265 -
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
|
N/A | |
Recruiting |
NCT05572307 -
Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty
|
||
Active, not recruiting |
NCT03629262 -
Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery
|
Phase 4 | |
Not yet recruiting |
NCT05537155 -
Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery
|
N/A | |
Completed |
NCT01964274 -
Relevance of the Peripheral Cholinesterase-activity on Neurocognitive Dysfunctions in Surgical Patients
|
||
Completed |
NCT01599689 -
Pilot and Feasibility Study of a Mirrors Intervention for Reducing Delirium in Older Cardiac Surgical Patients
|
N/A | |
Active, not recruiting |
NCT03291626 -
Postoperative Delirium: EEG Markers of Sleep and Wakefulness
|