Clinical Trials Logo

Clinical Trial Summary

Rapid palatal expansion aims at skeletally correcting the transverse maxillary deficiency by applying forces to separate the mid-palatal suture. In adult patients, the separation of the mid-palatal suture may not be possible due to its increased interdigitation. Miniscrew-assisted rapid maxillary expansion (MARPE) was proposed to transmit the forces directly to the mid-palatal suture through palatal miniscrews in addition to the anchor teeth. However, some non-growing patients may not respond favorably to MARPE. Hence, the use of corticopunctures as an adjunct to MARPE was recently proposed to overcome the increased resistance of the sutures in adult patients. The study aims to assess and compare the skeletal and dental effects of miniscrew-assisted rapid palatal expansion with and without corticopunctures in non-growing patients.


Clinical Trial Description

Rapid palatal expansion is a common treatment modality that aims at skeletally correcting the transverse maxillary deficiency by applying forces to separate the mid-palatal suture. In adult patients, the separation of the mid-palatal suture may not be possible due to its increased interdigitation and ossification. Miniscrew-assisted rapid maxillary expansion (MARPE) was proposed to transmit the forces directly to the mid-palatal suture through palatal miniscrews in addition to the anchor teeth. However, some non-growing patients may not respond favorably to MARPE. Hence, the use of corticopunctures as an adjunct to MARPE was recently proposed to overcome the increased resistance of the ossified mid-palatal sutures in adult patients. The aim of the study is to assess and compare the skeletal and dental effects of miniscrew-assisted rapid palatal expansion with and without corticopunctures in non-growing patients. A randomized clinical trial will be conducted to address the aim of the study. Patients will be randomly and equally assigned to group 1 (Corticopuncture-facilitated MARPE) or group 2 (Conventional MARPE). Both groups will be treated using Maxillary Skeletal Expander (MSE II, Biomaterials Korea Inc., Seoul, Korea). Ten corticopunctures will be made in group 1 along the mid-palatal suture with the aid of a 3D printed surgical guide. The skeletal and dental changes will be assessed using cone beam computed tomography scans obtained before treatment and after 6 months of expansion stabilization. The results will be compared between the groups and analyzed using the appropriate statistical tests. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05543460
Study type Interventional
Source Alexandria University
Contact Yomna M Yacout, MSC, PhD
Phone 2034868066
Email yomna.yacout@alexu.edu.eg
Status Recruiting
Phase N/A
Start date August 1, 2022
Completion date January 1, 2024

See also
  Status Clinical Trial Phase
Completed NCT02914431 - Personalized Titanium Plates vs CAD/CAM Surgical Splints in Maxillary Repositioning of Orthognathic Surgery N/A
Recruiting NCT05383820 - Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment Phase 4
Not yet recruiting NCT03794726 - Comparison of Orthodontic Molar Protraction With and Without Adjunctive Surgery N/A
Not yet recruiting NCT03513003 - The Use of a Pacifier to Correct Malocclusions in Young Children N/A
Completed NCT02603289 - One Week Aligner Evaluation
Completed NCT01463839 - Sleep Disorder and Oral Habits in Children N/A
Terminated NCT01210547 - Three-dimensional Assessment of Craniofacial Structures N/A
Recruiting NCT04946201 - Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet
Recruiting NCT04117360 - Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
Active, not recruiting NCT06291129 - Gingival Health and Malocclusion Among Type 1 Diabetic Children and Adolescents N/A
Recruiting NCT05684510 - Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy N/A
Completed NCT02659813 - Orthodontic Archwire Effectiveness Trial N/A
Completed NCT02427763 - Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device Phase 0
Completed NCT01962012 - Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners Phase 4
Completed NCT02267811 - The Effect of OrthoPulseā„¢ on the Rate of Orthodontic Tooth Movement N/A
Completed NCT03405961 - A Comparison of Conventional Versus Digital PAR (Peer Assessment Rating) Scores Using an Intraoral Scanner
Completed NCT05356780 - Predictability of Orthodontic Tooth Movement With Invisalign Aligners
Recruiting NCT06218641 - Discomfort Perceived by a Cohort of Patients Treated With Aligners and Attachments Placed According to Two Different Protocols N/A
Completed NCT05711160 - Comparison of the Accuracy and Reliability of Measurements Made on CBCT and IOS Images With Their made-on Plaster Models.
Recruiting NCT06140043 - Augmented Reality for Orthognatic Surgery Patient Education Phase 2/Phase 3