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Postbariatric Hypoglycemia clinical trials

View clinical trials related to Postbariatric Hypoglycemia.

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NCT ID: NCT06036784 Recruiting - Clinical trials for Postbariatric Hypoglycemia

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of MBX 1416 in Healthy Subjects

Start date: September 18, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple doses and Drug Drug Interaction of MBX 1416 in healthy volunteers This study includes 3 parts. Part A involves a single dose of MBX 1416 or placebo taken as a subcutaneous injection (SC). Part B involves repeat doses of MBX 1416 or placebo taken as a subcutaneous injection (SC). Part C involves the evaluation of rosuvastatin and acetaminophen pharmacokinetics in the presence and absence of MBX 1416.

NCT ID: NCT05721729 Active, not recruiting - Clinical trials for Postbariatric Hypoglycemia

Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions

Start date: June 23, 2023
Phase: Phase 2
Study type: Interventional

This is a phase 2 crossover, randomized, placebo-controlled, single-blind, repeat dose study in PBH subjects to determine the effect of mizagliflozin on adverse events and postprandial glucose excursions.

NCT ID: NCT05541939 Completed - Clinical trials for Postbariatric Hypoglycemia

Effect of Mizagliflozin on Postprandial Glucose and Insulin in Post-Bariatric Hypoglycemia Subjects

Start date: September 13, 2022
Phase: Phase 2
Study type: Interventional

This clinical study will examine the safety and tolerability, as well as the effects of orally administered mizagliflozin on post prandial glucose and insulin levels in subjects diagnosed with post-bariatric hypoglycemia (PBH).

NCT ID: NCT03373435 Completed - Clinical trials for Postbariatric Hypoglycemia

Safety and Efficacy of Exendin 9-39 in Patients With Postbariatric Hypoglycemia

PREVENT
Start date: March 19, 2018
Phase: Phase 2
Study type: Interventional

This clinical study will evaluate whether taking an investigational drug called exendin 9-39 is safe, well-tolerated, and helps to prevent low blood sugar in people who have had bariatric surgery and later develop a rare condition called postbariatric hypoglycemia (PBH).