Duloxetine Role in Reducing Opioid Consumption After Thoracotomy

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Clinical Trial Summary

A total of 60 patients scheduled for thoracotomy with the aim of excision of pleural or lung cancer, will be randomized by the use of a computer-generated table of random numbers to receive duloxetine 60 mg orally 2 hours before the surgical procedure and at 24 hours after the surgical procedure or a placebo pill following the same time schedule.

See also
	Status	Clinical Trial	Phase
	Completed	`NCT01726205` - Perioperative Pregabalin and Continuous Wound Infusion for Pain Control Following Thoracotomy	Phase 4
	Withdrawn	`NCT00934193` - Does Peri-Operative Gabapentin Reduce Chronic Post-Thoracotomy Pain?	Phase 3

NCT number	NCT03618225
Study type	Interventional
Source	Assiut University
Contact
Status	Completed
Phase	Phase 4
Start date	August 15, 2018
Completion date	January 31, 2020

Duloxetine Role in Reducing Opioid Consumption After Thoracotomy

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms