Post-Menopausal Women Clinical Trial
Official title:
The Effect of 12-week Supplementation With Olive Leaf Extract (OLE) on Body Composition and Muscle Strength, Skin-aging and Menopause-related Quality of Life in Postmenopausal Women (45-70 y); a Randomized Controlled Trial
Menopause is defined as the end of menstruation and fertility,starting 12 months after the last menstrual period.In this modern and economically developed society, most women are living for at least 20-40 years in a postmenopausal state. During menopause women may experience physical, emotional, and urogenital symptoms, with a significant impact on their health.Olive leaf extract supplementation may improve quality of life in post-menopausal women.
Menopause is associated with abdominal adipose tissue accumulation and the loss of muscle mass which causes a decrease in muscle strength. Moreover, the decrease in estrogens associated with menopause increases the risk of osteoporosis. The supplementation of oleuropein, the most abundant polyphenol found in olive tree leaves, can be an effective strategy to ameliorate body composition, due to its potential to attenuate the aging-induced decrease in protein content in muscles, to enhance thermogenesis in adipose tissue and to increase serum osteocalcin, a bone turnover marker. The current study wants to investigate the effect of 12-week olive leaf extract supplementation on body composition and muscle strength, skin-aging and menopause-related quality of life in postmenopausal women (45-70 y). ;
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