Post-concussion Syndrome & Chiropractic

Status Recruiting

Clinical Trial Summary

This proof-of-concept trial will explore the effects of manual chiropractic adjustments on nervous system function in individuals with post-concussion syndrome. This study will aim to recruit 10 individuals to receive 6 weeks of chiropractic care with 3 assessment periods. The participants will undergo a baseline assessment, mid-trial assessment, and post-trial assessment. The participants will wear an electroencephalography (EEG) cap for a neural assessment during an event related potential. They will wear electrical diodes to measure electrocardiography (ECG), impedance cardiography (ICG), and electrodermal activity (EDA) throughout the study and during an orthostatic challenge. Additional sensors will be placed on the participant to measure interlimb symmetry patterns during gait while walking on a treadmill.

Clinical Trial Description

Participants enrolled in the study will take a screening questionnaire to first determine eligibility. Once qualified, each individual will undergo a physical exam by a state licensed chiropractor to determine if there are any contraindications to undergo chiropractic care throughout the duration of the study. Each participant will receive 6 weeks of chiropractic care and will be assessed at weeks 0, 2, and 6 at the Dr. Sid E Williams Center for Chiropractic Research. Each participant will perform a number of tests to determine the evaluated function of their nervous system. In total, 3 different tests will be performed by the participant during an assessment visit that will take approximately 2.5 - 3 hours. During the assessments, each individual will be wearing electrical diodes to continually monitor ECG, ICG, and EDA. The specific assessments will be as follows: 1. Wearing an EEG net and then perform an event related potential after a baseline recording 2. Performing an orthostatic challenge while measuring ECG, ICG, and EDA 3. Wearing motion sensors while walking at a comfortable pace on a treadmill to evaluate interlimb symmetry and gait dynamics ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06151184
Study type	Interventional
Source	Life University
Contact	Austin Garlinghouse
Phone	7704262639
Email	research.studies@life.edu
Status	Recruiting
Phase	N/A
Start date	January 10, 2024
Completion date	December 31, 2024

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT05062148` - Fundamental and Applied Concussion Recovery Modality Research and Development: Applications for the Enhanced Recovery	N/A
Active, not recruiting	`NCT01874847` - PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin	Phase 2/Phase 3
Completed	`NCT01611194` - mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms	Phase 2
Recruiting	`NCT05328635` - Post-traumatic Headache Multidisciplinary Study
Active, not recruiting	`NCT03205215` - Hyperbaric Oxygen for Post Concussive Syndrome	N/A
Completed	`NCT03688984` - Treatment of Insomnia for Adolescents With Mild Traumatic Brain Injury	N/A
Recruiting	`NCT05889117` - Brain Stimulation for Concussion	N/A
Recruiting	`NCT04614922` - Acceptance and Commitment Therapy-based Rehabilitation of Post-concussion Symptoms	N/A
Recruiting	`NCT05072743` - Improvement in Sleep Symptomatology and Neurocognitive Function Using Photobiomodulation in Post-Concussion Patients	N/A
Completed	`NCT04681742` - Feasibility Testing of Cognitive Strategy Training in Post-Concussive Syndrome	N/A
Completed	`NCT03674398` - Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology	N/A
Active, not recruiting	`NCT05635656` - Digital Solutions for Concussion	N/A
Recruiting	`NCT05631301` - Move&Connect: A Program for Youth With Concussion and Their Caregivers.	N/A
Recruiting	`NCT06015451` - Exercise in Postconcussion Symptoms and Posttraumatic Headache	N/A
Terminated	`NCT03339037` - Hyperbaric Oxygen Therapy Effect on Post Concussion Syndrome in Children	N/A
Completed	`NCT03895450` - Treating Persistent Post-concussion Symptoms With Exercise	N/A
Recruiting	`NCT02089594` - Hyperbaric Oxygen Treatment to Treat Mild Traumatic Brain Injury (mTBI)/Persistent Post-Concussion Syndrome (PPCS)	Phase 3
Active, not recruiting	`NCT04568369` - Treatment of Post-concussion Syndrome With TMS: Using FNIRS as a Biomarker of Response	N/A
Recruiting	`NCT04688255` - Mobile Subthreshold Exercise Program for Concussion--R01	N/A
Not yet recruiting	`NCT05785000` - Rehabilitation in Post Concussion Syndrome	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Post-concussion Syndrome and Chiropractic — PCS

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms