Polypharmacy Clinical Trial
Official title:
Evaluation of a Pharmacist-Led Intervention to Reduce Drug-Related Problems in Patients Included in a Home Healthcare Program: A Pragmatic Randomized Clinical Trial
The investigators' hypothesis is that the individualized review of the pharmacotherapeutic plans of patients in a home healthcare program will be effective in improving the quality and safety of treatments. This study aims to evaluate the effectiveness of a standardized pharmaceutical intervention for the review and optimization of pharmacological treatments in ATDOM patients (catalan home healthcare program at primary care level), compared to the usual management.
ATDOM is the catalan home healthcare program at primary care level. Patients in home care program are frequently polymedicated, which entails a high risk of drug-related problems (DRPs). The investigators' hypothesis is that the individualized review of the pharmacotherapeutic plans of ATDOM patients will be effective in improving the quality and safety of treatments, reducing DRPs in terms of indication, adequacy, effectiveness, and safety. The main objective of this study is therefore to evaluate the effectiveness of a standardized pharmaceutical intervention for the review and optimization of pharmacological treatments in ATDOM patients, compared to the usual management. Specifically, the investigators want to determine, through a six-month intervention, the effectiveness in reducing DRPs per patient and polypharmacy. Additionally, the investigators will evaluate in the intervention group the implementation of the proposals for change or improvement by the responsible physician. This is a pragmatic randomized clinical trial with a comparable control group, with prospective follow-up of an intervention for the adequacy of the pharmacological treatment of patients in the ATDOM program assigned to primary care teams of the Camp de Tarragona Primary Care Directorate. PRMs, proposals and implementation will be determined. A descriptive statistical analysis will be carried out using multivariate adjustments. If the evaluation results are favorable, widespread implementation of the program would be possible. It could be extended to all ATDOM patients or outpatients in general. Thus, interdisciplinary teamwork would be strengthened to favor the health care continuum. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03688542 -
Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module
|
N/A | |
| Completed |
NCT02545257 -
Development of a Coordinated, Community-Based Medication Management Model for Home-Dwelling Aged in Primary Care
|
N/A | |
| Withdrawn |
NCT01932632 -
Medication Minimization for Long-term Care Residents
|
N/A | |
| Recruiting |
NCT04615065 -
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
|
||
| Active, not recruiting |
NCT04181879 -
Appropriate Polypharmacy in Older People in Primary Care
|
N/A | |
| Not yet recruiting |
NCT03283735 -
Deprescribing: a Portrait and Out-comes of the Reduction of Polypharmacy in Portugal
|
N/A | |
| Completed |
NCT02918058 -
Reducing Post-discharge Potentially Inappropriate Medications Among Older Adults
|
N/A | |
| Enrolling by invitation |
NCT05656560 -
Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges R01 Trial
|
N/A | |
| Completed |
NCT03655405 -
Randomised, Controlled Trial of an Individual Deprescribing Intervention for Nursing Homes Residents
|
N/A | |
| Completed |
NCT04575155 -
Development & Pilot of the Technology-Enabled Alliance for Medication Therapy Management
|
N/A | |
| Withdrawn |
NCT05816967 -
Rationalisation of Polypharmacy by the RASP-instrument and Discharge Counselling of Geriatric Inpatients
|
N/A | |
| Completed |
NCT05616689 -
Bundled Hyperpolypharmacy Deprescribing
|
N/A | |
| Terminated |
NCT04055896 -
Team Approach to Polypharmacy Evaluation and Reduction in a Long-Term Care Setting
|
N/A | |
| Active, not recruiting |
NCT03052192 -
Biological Aging, Medication, Malnutrition and Inflammation Among Acutely Ill and Healthy Elderly.
|
||
| Completed |
NCT02866799 -
Multi-PAP: Improving Prescription in Primary Care Patients With Multimorbidity and Polypharmacy
|
N/A | |
| Completed |
NCT01732302 -
Educational Intervention to Reduce Drug-related Hospitalizations in Elderly Primary Health Care Patients
|
N/A | |
| Enrolling by invitation |
NCT05053815 -
Pharmacogenomic Testing in a Program of All-inclusive Care for the Elderly (PACE) Setting
|
||
| Active, not recruiting |
NCT04585191 -
Reducing Treatment Risk in Older Adults With Diabetes
|
N/A | |
| Active, not recruiting |
NCT04120480 -
Effectiveness of PGx Testing
|
N/A | |
| Recruiting |
NCT05609981 -
Optimising Medication With Focus on Deprescribing in Frail Older People With Multidose Drug Dispensing Systems
|
N/A |