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Efficacy of Metformin in PCOS: Metabolic and Hormonal Factors

Polycystic Ovary Syndrome Clinical Trial

Clinical Trial Summary

Hypothesis: Metformin treatment normalises hormone values and metabolic parameters in women with PCOS. Ovulation is restored and bleeding periods become regular.

Fifty women with PCOS (Rotterdam criteria) are randomised to either placebo or metformin for 6 months. After a wash-out period of 3 months, the opposite treatment is given for another 6 months. Measurements are performed before ech treatment period, every second month during treatment and after completing treatment.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00317928
Study type Interventional
Source Aarhus University Hospital Skejby
Contact
Status Active, not recruiting
Phase N/A
Start date August 2001
Completion date September 2004
View Details
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