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NCT04826848 Clinical Trial

Lactate Clearance in Hospital-acquired Pneumonia

Pneumonia Clinical Trial

Official title:
The Prognostic Value of Lactate Clearance in Hospital-acquired Pneumonia

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04826848
Other study ID # LC-HAP
Secondary ID
Status Completed
Phase
First received
Last updated
Start date June 1, 2019
Est. completion date December 1, 2019

Study information
Verified date March 2021
Source Ankara City Hospital Bilkent
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

There is no clear consensus on the use of pneumonia severity index (PSI) developed for community-acquired pneumonia in hospital-acquired pneumonia cases. In another aspect, PSI is a relatively difficult scoring system that includes many parameters. This study evaluated whether lactate clearance could be used as a mortality marker instead of PSI in hospital-acquired pneumonia. As a result, lactate clearance was lower in the mortal group and when the diagnostic statistics were evaluated, it was seen that the sensitivity and specificity rates were significantly higher. In conclusion, lactate clearance has been evaluated as a strong predictor of mortality in hospital-acquired pneumonia.

Recruitment information / eligibility
Status Completed
Enrollment 69
Est. completion date December 1, 2019
Est. primary completion date December 1, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - 18 and over age, hospital-acquired pneumonia, emergency department admissions Exclusion Criteria: - Patients who are pregnant or lactating, under 18 years of age, in the healthcare-associated pneumonia group, had mechanical ventilation at the last hospitalization, whose lactate level could not be studied for any reason at admission and 6th hour, had missing data used in pneumonia severity index calculation and/or who did not accept to participate in the study

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Lactate
We will evauate the lactate clearance of the patients in 6 hours period. Lactate clearance = [(Initial lactate - 6th hour lactate) / Initial lactate] * 100

Locations
Country Name City State
Turkey Ankara Yildirim Beyazit University, School of Medicine, Department of Emergency Medicine Ankara Çankaya

Sponsors (1)
Lead Sponsor Collaborator
Ankara City Hospital Bilkent

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary Mortality 28-day mortality 28 day
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