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NCT04424355 Clinical Trial

Magnetic Resonance Imaging to Detect Signs of Viral Pneumonia in Patients With Coronavirus Infection.

Pneumonia Clinical Trial

Official title:
Possibilities of Chest Magnetic Resonance Imaging (MRI) in Diagnostics of COVID-19. The Use of MRI to Assess Lung Damage in Patients With Coronavirus Infection

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04424355
Other study ID # 2020-2
Secondary ID
Status Completed
Phase
First received
Last updated
Start date May 19, 2020
Est. completion date December 20, 2021

Study information
Verified date March 2023
Source Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Since the onset of the COVID-19 pandemic, the importance of chest computed tomography (CT) in detecting signs of viral pneumonia has become clear from the literature. However, the increased patient flow creates an additional pressure on CT centers. We believe, the use of chest magnetic resonance imaging (MRI) can help to test patients for CОVID-19 when CT scan is not available. Lung MRI may be useful in routing a patient in a difficult epidemiological situation.

Description:

Currently, with increased load of CT studies, alternative methods of viral pneumonia signs' visualization are required. Investigators hypothesize that chest MRI could be a test for detecting pulmonary features of COVID-19. They consider using MRI to assess COVID-19 viral pneumonia. Absence of radiation exposure to patients is a clear advantage of MRI. This is a prospective, observational cohort study assessing patients with suspected COVID-19. It's primary goal is to determine the ability of multiparametric MRI to detect lung abnormalities - ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis - in comparison to CT scan. In this study each patient with suspected pneumonia will sequentially undergo both chest CT and MRI during his/her visit. Scan protocols will be identical for each patient. Each participants completed an online questionnaire.

Recruitment information / eligibility
Status Completed
Enrollment 25
Est. completion date December 20, 2021
Est. primary completion date July 19, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - A referral from the attending physician for a chest CT scan - Suspected pneumonia - Signed informed consent - Over 18 years old Exclusion Criteria: - Pregnant or nursing women - Presence of foreign implanted objects in the body at the scan level (including cardiac pacemakers, spine metalware)

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Chest MRI
Patients referred by the primary care physician with suspected pneumonia

Locations
Country Name City State
Russian Federation Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department Moscow

Sponsors (1)
Lead Sponsor Collaborator
Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department

Country where clinical trial is conducted

Russian Federation, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of zones of pulmonary parenchyma corresponding to viral pneumonia detected by chest MRI in comparison with CT scan Expected number - more than two zones Upon completion, up to 1 year
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