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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT03790176
Other study ID # Version 2.2 April 19, 2018
Secondary ID
Status Recruiting
Phase Phase 1
First received
Last updated
Start date October 1, 2018
Est. completion date December 2022

Study information

Verified date August 2021
Source Medical University of Vienna
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

CAZ/AVI is a new antibiotic drug that is meant to be used for various indications including cIAI and nosocomial pneumonia. To date, limited data exists on PK of CAZ/AVI in patients undergoing peritoneal dialysis as well as on penetration of CAZ/AVI in ELF of critically ill patients. The present study is carried out to determine target site PK of CAZ/AVI in these two populations, in order to contribute to a more complete understanding of the drug's penetration to its site of action.


Description:

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Study Design


Related Conditions & MeSH terms


Intervention

Drug:
Intravenous Infusion
see arm/group description. NO INTERVENTION IN STUDY GROUP B! PATIENTS OF GROUP B WILL RECEIVE CAZ/AVI INDEPENDENTLY FROM STUDY PARTICIPATION BASED ON DECISION OF THEIR TREATING PHYSICIAN

Locations

Country Name City State
Austria Medical University of Vienna Vienna

Sponsors (1)

Lead Sponsor Collaborator
Markus Zeitlinger

Country where clinical trial is conducted

Austria, 

Outcome

Type Measure Description Time frame Safety issue
Primary Area under the concentration time curve (AUC) from 0 to 8 hours (AUC0-8) on study days
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