Pneumonia Clinical Trial
— OPPAÎOfficial title:
Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia
Hypoxemic pneumonia is a major cause of hospitalization in Pulmonology. The patient's dependency on oxygen prevents early discharge from the hospital. An automated oxygen therapy is a system that allows administration of oxygen with a flow that is automatically adjusted to the patient's saturation, which is continuously monitored. This system has proven to be particularly effective with chronic obstructive pulmonary disease (COPD) patients, by decreasing the time spent in hypoxia and hyperoxia, and by accelerating the weaning of oxygen. Our hypothesis is that automated oxygen therapy leads to a diminution on the length of hospital stay.
Status | Recruiting |
Enrollment | 128 |
Est. completion date | October 2024 |
Est. primary completion date | October 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Adult - Patient living at home or in an institution - Patient hospitalized for less than 48 hours - Pneumonia defined (according to the 2006 French-speaking infectious pneumology society (SPILF) criteria) by: - respiratory functional symptoms (cough, sputum, dyspnea, chest pain) and - Hyperthermia >38,5°C or hypothermia <36°C and - Radiological Signs of Pneumonia - Hypoxia : SpO2 < 94% in ambient air and/or PaO2< 60 mmHg in ambient air Exclusion Criteria: - Pneumonia acquired at the hospital. - Patient hospitalized in another department more than 48 hours before admission - Chronic respiratory failure - Active neoplasia - Patients undergoing oxygen therapy and / or long-term NIV - Associated cardiac decompensation (clinical signs and / or NTproBNP> 1800ng / mL) (3 - Initial Need for high flow oxygen therapy or ventilatory support (NIV, VI) - Difficulties expected from home support. |
Country | Name | City | State |
---|---|---|---|
France | CHU Larrey | Toulouse |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Toulouse |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Length in days of hospital stay | measure of total days of hospitalization and intensive care | 1 month | |
Secondary | Duration of oxygen therapy | Oxygen therapy time evaluation during hospitalization of patient | 1 month | |
Secondary | Time spent outside of the target saturation | Investigator want evaluate the time spent outside of the target saturation by patient, during their hospitalization, | 1 month | |
Secondary | the cost on the medical-economic level | investigator want evaluate the cost of hospitalization between patient in arm "Automated oxygen therapy" and patient in arm "Standard Oxygen therapy" | 1 month | |
Secondary | rate of medical complication | Investigator want to evaluate the rate of medical complication between patient in arm "Automated oxygen therapy" and patient in arm "Standard Oxygen therapy" | 1 month | |
Secondary | quality questionnaire of patient's life during hospitalization | Investigator want to evaluate the quality of life during hospitalization between patient in arm "Automated oxygen therapy" and patient in arm "Standard Oxygen therapy" | 1 month |
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