5 Years Mortality-rate in Patients Treated for Severe Pneumonia in an ICU - a Retrospective Study

Pneumonia Clinical Trial

— pneumonia  

Official title:

Cause-specific 5 Years Mortality-rate in Patients Treated for Severe Pneumonia in an ICU - a Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02212093
• Other study ID #: 2013/2338
• Status: Completed
• Phase: N/A
• First received: August 7, 2014
• Last updated: July 22, 2015
• Start date: June 2014
• Est. completion date: February 2015

Study information

• Verified date: July 2015
• Source: University Hospital, Akershus
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway: Regional Ethics Commitee
• Study type: Observational

Clinical Trial Summary

Severe pneumonia has a high in-hospital mortality. There are few studies which investigate the long-term mortality in patients that are discharged alive from the hospital. In this study we want to investigate the 5 years mortality after treatment of severe pneumonia in an ICU. We will also investigate the cause of death after discharge from the hospital.

Description:

Patients with severe pneumonia who need treatment in an ICU have a high in-hospital mortality (16-46%). There are few studies which investigate the long-term mortality (> 1year) in patients after discharge from the hospital. There seems to be a higher mortality in this group compared to the general population. The cause(s) of this higher long-term mortality is unclear and few studies have investigated this problem.

We are going to investigate the 5 years mortality rate in this population of patients. We are also going to investigate the cause of death in the patients who are discharged from the hospital alive.

Inclusion criteria: Patients > 18 years. Primary diagnose: pneumonia, and the need of mechanical ventilation for at least 24 hours in an ICU. The patients who arrive at the ICU in Akershus University Hospital in the period from 01.01.1997 to 31.12.2006.

The datas are collected from the patients' journals and the local ICU register. Collecting data: Age, sex, comorbidity, SAPSII, mechanical ventilation time, stay in the ICU, stay in the hospital, ICU mortality, hospital mortality, 5 years mortality, type of pneumonia (bacteriology).

Time of death after discharge is collected from Norwegian National Registry. Cause of death after discharge is collected from Norwegian Institute of Public Health.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 236
• Est. completion date: February 2015
• Est. primary completion date: February 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients > 18 years. Primary diagnose: pneumonia, and the need of mechanical ventilation for at least 24 hours in an ICU. The patients who arrived the ICU in Akershus University Hospital in the period from 01.01.1997 to 31.12.2006.

Exclusion Criteria:

• Patients < 18 years. Patients with need for mechanical ventilation < 24 hours

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

• Pneumonia

Locations

Country	Name	City	State
Norway	Akershus University Hospital	Nordbyhagen	Akershus

Sponsors (2)

Lead Sponsor	Collaborator
University Hospital, Akershus	Oslo University Hospital

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	5 years mortality		5 years	No
Secondary	cause of death after discharge from the hospital		5 years	No