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Trimethoprim/Sulfamethoxazole Combined With Caspofungin as First-line Therapy in PCP

Pneumocystis Pneumonia Clinical Trial

Official title:
A Prospective Randomized Controlled Study to Compare Efficacy of Caspofungin Combined With Trimethoprim-sulfamethoxazole Versus Trimethoprim/Sulfamethoxazole as First-line Therapy in Non-HIV Patients With Severe Pneumocystis Pneumonia

Clinical Trial Summary

This is a prospective, randomized clinical trial. During the study, non-HIV patients who are admitted to ICU due to Pneumocystic pneumonia (PCP) and have not received anti-PCP therapy or have received therapy less than 48hrs will be randomized (1:1) to received caspofungin combined with trimethoprim-sulfamethoxazole or trimethoprim-sulfamethoxazole alone.

The aim of this study is to compare the effectiveness of caspofungin combined with trimethoprim-sulfamethoxazole with that of conventional therapy (trimethoprim-sulfamethoxazole alone) as first-line therapy in the treatment of severe Pneumocystis pneumonia (PCP) in non-HIV patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03978559
Study type Interventional
Source Peking Union Medical College Hospital
Contact Bin Du
Phone 0086-10-69155036
Email dubin98@gmail.com
Status Recruiting
Phase Phase 4
Start date August 14, 2019
Completion date July 8, 2022
View Details
See also
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